The rapid growth of a pleomorphic adenoma of the parotid gland in the third trimester of pregnancy.

Introduction: We report a case highlighting the multidisciplinary management of a giant pleomorphic adenoma of the parotid gland that showed rapid growth in the third trimester of pregnancy.

Case Presentation: A 43-year-old Caucasian woman presented in her 32nd week of gestation with a tumor of the parotid gland. Ultrasonography of her neck showed a parotid lesion of 40 × 30 × 27.

Smoking impairs angiogenesis during maturation of human oocytes.

Objective: This study determines whether smoking influences ovarian vascularization which thus may impair follicular development.

Design: Prospective laboratory study of follicular fluids and granulosa cells from patients undergoing in vitro fertilization.

Setting: University Hospital Aachen, Germany.