Publications by authors named "Frederike M D Husmann"
Article Synopsis
- This study investigated whether prebiotic fibers, specifically galacto-oligosaccharides (GOS) and fructo-oligosaccharides (FOS), can enhance iron absorption from high doses of iron supplements (ferrous fumarate) in iron-depleted women.
- Results showed that both GOS and FOS significantly increased fractional iron absorption by about 45% and 51%, respectively, compared to a control group, while acacia gum had no significant effect.
- The findings suggest that GOS and FOS could be beneficial for improving iron absorption, providing an additional 10-12 mg of absorbed iron when taken with a 100 mg iron dose.
Iron deficiency remains the most common nutritional deficiency. Oral iron supplementation is the recommended first-line treatment and used as a preventive measure as well. Enhancers of iron absorption are highly sought after to improve supplementation outcomes.
View Article and Find Full Text PDFBackground: Prebiotic galacto-oligosaccharides (GOS) increase iron absorption from fortification-level iron doses given as ferrous fumarate (FeFum) in women and children. Whether GOS or other fibers, such as prebiotic fructo-oligosaccharides (FOS) and acacia gum, increase iron absorption from higher supplemental doses of FeFum is unclear.
Objectives: In iron-depleted [serum ferritin (SF) <25 μg/L] women, we tested if oral coadministration of 15 g GOS, FOS, or acacia gum increased iron absorption from a 100 mg Fe supplement given as FeFum.
Background: Prebiotic galacto-oligosaccharides (GOS) are novel enhancers of iron absorption from ferrous fumarate (FeFum). However, the mechanism(s) of this effect, and whether it occurs in the proximal or distal gut, are uncertain.
Objectives: We studied: 1) in vitro, the effect of GOS on iron solubility and dialyzability from FeFum; 2) in volunteers, the absorption kinetics of FeFum given with and without GOS using stable isotope appearance curves (SIAC).