Publications by authors named "Frederik Wilhelm Ott"
Article Synopsis
- - The study investigates how long-term treatment with the cannabinoid WIN 55,212-2 affects brain metabolism and memory in healthy mice, emphasizing the need to understand cannabis effects on behavior.
- - Results show that WIN 55,212-2 reduces glucose metabolism in key brain regions (like the hippocampus) and leads to memory deficits, particularly when administered during early adulthood.
- - The findings highlight serious risks associated with prolonged WIN 55,212-2 use, adding to the understanding of chronic cannabinoid exposure’s impact on brain function and behavior.
The presynaptic protein Mover/TPRGL/SVAP30 is absent in and and differentially expressed in synapses in the rodent brain, suggesting that it confers specific functions to subtypes of presynaptic terminals. In order to investigate how the absence of this protein affects behavior and learning, Mover knockout mice (KO) were subjected to a series of established learning tests. To determine possible behavioral and cognitive alterations, male and female 8-week-old KO and C57Bl/6J wildtype (WT) control mice were tested in a battery of memory and anxiety tests.
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