Does an integrated boost increase acute toxicity in prone hypofractionated breast irradiation? A randomized controlled trial.

Background And Purpose: The safety of a simultaneous integrated boost (SIB) in combination with prone hypofractionated whole-breast irradiation (WBI) was investigated.

Materials And Methods: 167 patients were randomized between WBI with a sequential boost (SeB) or SIB. All patients were treated in prone position to 40.

Hypofractionated whole breast irradiation for patients with large breasts: a randomized trial comparing prone and supine positions.

Background And Purpose: Comparison of acute toxicity of whole-breast irradiation (WBI) in prone and supine positions.

Materials And Methods: This non-blinded, randomized, prospective, mono-centric trial was undertaken between December 29, 2010, and December 12, 2012. One hundred patients with large breasts were randomized between supine multi beam (MB) and prone tangential field (TF) intensity modulated radiotherapy (IMRT).