Optimized molecule detection in localization microscopy with selected false positive probability.

Single-molecule localization microscopy (SMLM) allows imaging beyond the diffraction limit. Detection of molecules is a crucial initial step in SMLM. False positive detections, which are not quantitatively controlled in current methods, are a source of artifacts that affect the entire SMLM analysis pipeline.

Postoperative prophylactic antibiotics were not associated with decreased surgical site infections following hemilaminectomy in dogs: a retrospective study.

Objective: To compare hemilaminectomy surgical site infection (SSI) rates in dogs treated with or without postoperative prophylactic antibiotics.

Methods: Medical records of 275 client-owned dogs from 1 tertiary referral hospital were retrospectively reviewed for dogs treated with thoracolumbar hemilaminectomy for intervertebral disk herniation between 2018 and 2023. Dogs were grouped according to whether they were treated with prophylactic postoperative antibiotics (group A) or not (group B).

Correction: Barkjohn et al. Correction and Accuracy of PurpleAir PM Measurements for Extreme Wildfire Smoke. 2022, , 9669.

In the original publication [...

Liposomal bupivacaine was not associated with increased postoperative complications in dogs receiving closed anal sacculectomy: a retrospective study.

Objective: To compare the postoperative complication rates of anal sacculectomy procedures in dogs treated with or without liposomal bupivacaine (LB).

Methods: Medical records of 397 client-owned dogs treated with closed anal sacculectomy between 2016 and 2023 were retrospectively identified and grouped on the basis of administration of LB (LB group) or not (non-LB group). Details of short-term (< 15 days) postoperative complications were recorded from physical examination and client communication notes as well as referral documents and compared between groups.

Cognitive reflection is a distinct and measurable trait.

We report the findings of an adversarial collaboration examining whether the cognitive reflection test (CRT) measures anything beyond mathematical aptitude and, if so, whether its incremental predictive validity can be attributed to reflection, per se. We found that an 8-item CRT has greater predictive validity than an 8-item Mathematical Aptitude Test (MAT) consisting of comparably difficult items which lack dominant intuitive lures. Further, the incremental predictive validity stems from the CRT's measurement of reflection, which we show using both structural equation models and a dual-response paradigm that helps distinguish susceptibility to intuitions from inadequate mathematical aptitude.

Secondary fastener (tape) placement on a blood pressure cuff causes interindividual Doppler blood pressure measurement variability in healthy large-breed dogs.

Objective: The objective of this study was to compare Doppler blood pressure (DBP) measurements between blood pressure cuffs (BPCs) with and without a secondary fastener (tape) in healthy nonanesthetized large-breed dogs.

Animals: 28 healthy dogs.

Methods: Superficial palmar venous arch DBP measurements with and without tape on the BPC were performed in lateral recumbency with Doppler ultrasound.

Preliminary evaluation of a novel method for computed tomography quantification of lumbosacral articular process displacement in dogs with and without degenerative lumbosacral stenosis.

Objective: This study aimed to describe the diagnostic discrimination and reliability of a novel technique for quantifying lumbosacral articular process displacement (LSAPD) on dorsal plane computed tomography (DPCT) imaging in dogs with and without degenerative lumbosacral stenosis (DLSS).

Study Design: DPCT surveys of the lumbosacral vertebral column were performed with dogs positioned in extension and flexion. LSAPD is defined as the distance between the cranial aspects of the L7 and S1 articular processes.

Photobiomodulation therapy using a class 3b laser does not cause premature rupture of multivesicular liposomal bupivacaine suspensions in a cadaver model.

Objective: To determine if photobiomodulation causes a premature release of liposomal bupivacaine (LB) suspensions.

Animals: A 25-kg mixed breed dog cadaver euthanized for reasons unrelated to this study.

Methods: In September 2022, a proximomedial tibial incision was made in a dog cadaver, and a tibial plateau leveling osteotomy plate was implanted.

Results of routine thoracic radiographic examinations rarely impact the plan to proceed with anesthetic procedures in dogs with presumed acute intervertebral disc herniation.

Introduction: Acute thoracolumbar intervertebral disc herniation (IVDH) constitutes an emergency because associated neurological clinical signs can be progressive, with prognosis dependent on preoperative presence of deep pain perception. Pre-anesthetic thoracic radiographs are routinely performed to evaluate for potential pathology that could result in increased risk or change in overall prognosis. However, due to the emergent nature of this disease, the weight of thoracic radiographic findings on treatment plans for these dogs in unknown.

A Digital Intervention to Improve Skin Self-Examination Among Survivors of Melanoma: Protocol for a Type-1 Hybrid Effectiveness-Implementation Randomized Trial.

Background: Although melanoma survival rates have improved in recent years, survivors remain at risk of recurrence, second primary cancers, and keratinocyte carcinomas. The National Comprehensive Cancer Network recommends skin examinations by a physician every 3 to 12 months. Regular thorough skin self-examinations (SSEs) are recommended for survivors of melanoma to promote the detection of earlier-stage, thinner melanomas, which are associated with improved survival and lower treatment costs.

The Effects of a Parent-Focused Social Media Intervention on Child Sun Safety: Pilot and Feasibility Study.

Background: Middle childhood (ages 8-12 years) is a critical period for forming behavioral habits and reducing the risk for the development of skin cancer later in life. During this time, children develop more autonomy and spend more unsupervised time away from their parents. Professional agencies recommend that all children engage in regular sun protection behaviors and avoid the sun during peak daytime hours.

Spontaneous pneumothorax in a dog with a history of successfully treated heartworm disease: A case report.

Objective: To describe a dog presented with spontaneous pneumothorax secondary to chronic pulmonary changes associated with a history of resolved canine heartworm disease.

Case Or Series Summary: A 7-year-old 25.2kg female spayed German Shepherd mix was presented for management of spontaneous pneumothorax.

The formation and revision of intuitions.

This paper presents 59 new studies (N = 72,310) which focus primarily on the "bat and ball problem." It documents our attempts to understand the determinants of the erroneous intuition, our exploration of ways to stimulate reflection, and our discovery that the erroneous intuition often survives whatever further reflection can be induced. Our investigation helps inform conceptions of dual process models, as "system 1" processes often appear to override or corrupt "system 2" processes.

Prevalence and correlates of fear of recurrence among oral and oropharyngeal cancer survivors.

Purpose: Fear of recurrence (FoR) is a prevalent and difficult experience among cancer patients. Most research has focused on FoR among breast cancer patients, with less attention paid to characterizing levels and correlates of FoR among oral and oropharyngeal cancer survivors. The purpose was to characterize FoR with a measure assessing both global fears and the nature of specific worries as well as evaluate the role of sociodemographic and clinical factors, survivorship care transition practices, lifestyle factors, and depressive symptoms in FoR.

The effect of two platelet-rich plasma aspiration techniques on plasma cellular concentrations using a double syringe gravitational centrifugation system.

Objective: To identify which aspiration technique increased plasma platelet concentration and which technique minimized plasma leukocyte and erythrocyte concentrations using a gravitational double-syringe platelet rich plasma (PRP) system.

Study Design: Controlled laboratory study.

Animals: Thirty adult dogs.

Factors associated with health-related quality of life in a cohort of cancer survivors in New Jersey.

Background: Although there is extensive literature on correlates of health-related quality of life (HRQoL) among cancer survivors, there has been less attention paid to the role of socioeconomic disadvantage and survivorship care transition experiences in HRQoL. There are few large cohort studies that include a comprehensive set of correlates to obtain a full picture of what is associated with survivors' HRQ0L. This cohort study of recent cancer survivors in New Jersey aimed to explore the association between social determinants of health, health history, health behaviors, survivorship care experiences, and psychosocial factors in HRQoL.

D-penicillamine-associated neutropenia in a Doberman pinscher.

Copper-associated hepatitis in dogs results from elevated copper levels secondary to increased intake or decreased clearance. Treatment is through establishing a negative copper balance and can include chelation therapy. Traditionally, chelation therapy in dogs is uses D-penicillamine, which has been shown to have severe side effects in humans.

Facebook Intervention for Young-Onset Melanoma Survivors and Families: Protocol for a Randomized Controlled Trial.

Background: Individuals diagnosed with melanoma before the age of 40 years (young-onset melanoma survivors) and their first-degree relatives (FDRs) are a growing population at risk for developing recurrent melanoma or new melanomas. Regular surveillance using clinical skin examination (CSE) and skin self-examination (SSE) and engagement in preventive behaviors including sun protection are recommended. Given the growing population of survivors and their families who are at increased risk, it is surprising that no behavioral interventions have been developed and evaluated to improve risk-reduction behaviors.

Enhancing Self-care Among Oral Cancer Survivors: Protocol for the Empowered Survivor Trial.

Background: Survivors of oral cavity and oropharyngeal cancer frequently experience difficulties in swallowing; tasting; speaking; chewing; and maintaining comfortable movements of the head, neck, and shoulder. Engagement in regular self-care can reduce further loss of function and mitigate late effects. Despite the substantial self-care requirements, there are no empirically based interventions to enhance the skills and confidence of these survivors in managing their ongoing care.

Correction and Accuracy of PurpleAir PM Measurements for Extreme Wildfire Smoke.

PurpleAir particulate matter (PM) sensors are increasingly used in the United States and other countries for real-time air quality information, particularly during wildfire smoke episodes. Uncorrected PurpleAir data can be biased and may exhibit a nonlinear response at extreme smoke concentrations (>300 µg/m3). This bias and nonlinearity result in a disagreement with the traditional ambient monitoring network, leading to the public’s confusion during smoke episodes.

The effect of grip location on Kirschner wire bend characteristics: An in vitro study.

Objective: To determine the effect of Kirschner wire (K-wire) grip location on bend angle, bend radius, and torque when performing a Z-bend technique.

Study Design: Experimental study.

Sample Population: Ten samples at each of five grip locations for each of three K-wire diameters.

Living with the Threat of Covid-19: Exploring the Psychological Impact of Covid-19 in Those who Conceived Through ART Versus Spontaneously.

Objectives: To explore and compare anxiety relating to the threat of Covid-19 in pregnancy by women who conceived through assisted reproductive technology (ART) and spontaneously. We also examined the psychological coping strategies used and lived experience for both groups.

Methods: A total of 21 women who conceived through ART at a private university based IVF and a matched sample of women who conceived spontaneously were enrolled from July 2020 to February 2021.

Self-efficacy in managing post-treatment care among oral and oropharyngeal cancer survivors.

Objective: Physical and psychosocial effects of oral cancer result in long-term self-management needs. Little attention has been paid to survivors' self-efficacy in managing their care. Study goals were to characterise self-care self-efficacy and evaluate socio-demographics, disease, attitudinal factors and psychological correlates of self-efficacy and engagement in head and neck self-exams.

Candidate Tidal Disruption Event AT2019fdr Coincident with a High-Energy Neutrino.

The origins of the high-energy cosmic neutrino flux remain largely unknown. Recently, one high-energy neutrino was associated with a tidal disruption event (TDE). Here we present AT2019fdr, an exceptionally luminous TDE candidate, coincident with another high-energy neutrino.

Diagnosis and Conservative Management of Primary Lymphedema Resulting From Multiple Aplastic Lymphocenters in a Dog.

A 6-week-old 7.4-kg (16.3-lb) sexually intact male Great Dane with a history of severe peripheral edema within the head, neck, limbs, and tail since birth was referred for further evaluation.