Case report: management of persistent dural anastomotic dehiscence in a patient treated with bevacizumab.

A 55-year-old woman with recurrent glioblastoma multiforme on palliative chemotherapy including Avastin, an angiogenesis inhibitor, presents with several episodes of bacterial meningitis secondary to a persistent cerebrospinal fluid (CSF) leak. Anastomotic dehiscence of the dura mater in the region of the previous craniotomy sites was evident. Attempts to repair the cranial CSF leak with external ventricular drain and ventriculoperitoneal shunt were unsuccessful.

Paraumbilical block for umbilical herniorraphy.

Background: Umbilical herniorraphy is a common paediatric surgery day case. Paraumbilical blocks have previously been reported to provide excellent analgesia for umbilical hernia repairs.

Methods: Local anaesthesia through a paraumbilical block was compared with local infiltration.