Publications by authors named "Frederick Dhermain"
Article Synopsis
- - The study analyzed the outcomes of patients with newly diagnosed WHO grade III oligodendroglioma who were divided into three treatment groups: radiotherapy alone, radiotherapy with temozolomide (TMZ), and TMZ alone.
- - Results showed that patients receiving TMZ alone had a significantly shorter progression-free survival (PFS) compared to those receiving radiotherapy, with 83.3% of the TMZ group experiencing disease progression.
- - Although overall survival (OS) did not differ significantly among the groups, the ongoing CODEL trial is being redesigned to further compare radiotherapy combined with different chemotherapy options (PCV vs TMZ).
The European Association for Neuro-Oncology guideline provides recommendations for the clinical care of adult patients with astrocytic and oligodendroglial gliomas, including glioblastomas. The guideline is based on the 2016 WHO classification of tumours of the central nervous system and on scientific developments since the 2014 guideline. The recommendations focus on pathological and radiological diagnostics, and the main treatment modalities of surgery, radiotherapy, and pharmacotherapy.
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