Publications by authors named "Frederic Neumann"
Article Synopsis
- - The study analyzed characteristics, treatment approaches, and outcomes of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA) in 1,075 patients over 12 years, noting significant differences and similarities between the two cancers.
- - Findings indicated that HCC patients generally presented with earlier-stage disease and had a higher prevalence of cirrhosis (89%), while iCCA patients were more likely to be female and had fewer cirrhosis cases (34%).
- - Overall survival rates revealed HCC patients lived longer (18.4 months) compared to iCCA patients (7.0 months), with specific molecular alterations found in half of the iCCA cases, highlighting potential new treatment
In France, determination of the mutation status of RAS genes for predictive response to anti-EGFR targeted treatments is carried out by public platforms of molecular biology of cancer created by the French National Cancer Institute. This study aims to demonstrate the feasibility of these analyses by a private pathology laboratory (MEDIPATH) as per the requirements of accreditation. We retrospectively studied the mutation status of KRAS and NRAS genes in 163 cases of colorectal metastatic cancer using the Cobas technique.
View Article and Find Full Text PDFPrimary neuroendocrine carcinoma arises mainly in the gastrointestinal tract, lungs and pancreas, localization in the fallopian tube is exceptional with only one case being reported in literature. This second case concerns a 54-year-old patient, diagnosed at the Pierre-Zobda-Quitman hospital. Tumor histology revealed a poorly differentiated carcinoma with medium to large cells, marked atypia and high mitotic activity.
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