Publications by authors named "Frederic Mascarelli"
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Synopsis of recent research by authors named "Frederic Mascarelli"
- Frederic Mascarelli's recent research primarily focuses on ocular health, particularly conditions such as Fuchs endothelial corneal dystrophy (FECD) and age-related macular degeneration (AMD), emphasizing the molecular and cellular mechanisms underlying these diseases.
- His studies utilize advanced techniques such as chromatic confocal microscopy and shotgun proteomics to investigate corneal endothelial characteristics and the impact of genetic factors like the TCF4 gene on disease progression in FECD patients.
- Mascarelli's research also explores the role of amyloid-beta in retinal neurodegenerative processes, drawing parallels between retinal diseases and Alzheimer’s disease, thereby highlighting the shared pathological mechanisms of oxidative stress and amyloidosis.
