Multiple Intramyocardial Masses in an Otherwise Healthy 35-Year-Old Woman.

Sarcoidosis with manifest cardiac involvement typically presents with heart failure, conduction abnormalities, or ventricular arrhythmias. Here, we present a case of a young woman whose presentation raised suspicion for metastatic cardiac disease of unknown primary origin. Further investigation revealed cardiac sarcoidosis with multiple intramyocardial granulomatous masses in the absence of significant enlargement of hilar or mediastinal nodes.

Exercise and arrhythmic risk in TMEM43 p.S358L arrhythmogenic right ventricular cardiomyopathy.

Background: High-level exercise has been associated with a malignant phenotype in desmosomal and genotype-negative forms of arrhythmogenic right ventricular cardiomyopathy (ARVC). This is the first study to examine this issue with ARVC secondary to the TMEM43 p.S358L mutation.

QT prolongation and monomorphic VT caused by pheochromocytoma.

Introduction: Pheochromocytoma may present with ECG abnormalities as one of the few clues to the diagnosis.

Methods And Results: A 30-year-old woman presented with chest pain and a QTc of 525 ms. Four weeks later following a syncopal episode, her QTc was 660 ms.

Management of infections involving implanted cardiac electrophysiologic devices.

Indications for cardiac electrophysiologic device implantation have expanded, and the target demographic has widened. Unfortunately, these changes have been accompanied by an increase in cardiac device-associated infections out of proportion to the increase in implantation rate. Diagnosing a cardiac device infection may be challenging because of the spectrum of clinical manifestations, ranging from isolated generator pocket pain to frank sepsis with clear evidence of endocarditis.