Pharmacokinetics, pharmacodynamics and local tolerance at injection site of marbofloxacin administered by regional intravenous limb perfusion in standing horses.

Objective: To evaluate pharmacokinetic-pharmacodynamic variables and local tolerance at injection-site of marbofloxacin administered via regional intravenous limb perfusion (RIVLP) in standing horses.

Animals: Adult horses (n = 6).

Methods: RIVLP were performed with rubber tourniquets applied to the forelimbs of standing sedated horses.