Publications by authors named "Freddy Villanueva-Cotrina"

Article Synopsis
  • Candidemia, a dangerous fungal infection, is becoming more common in cancer patients, linking high mortality rates to biofilm-producing strains of Candida, which may resist antifungal treatment.
  • A study of 140 cancer patients in Peru examined the impact of biofilm formation on mortality by comparing treated and untreated individuals over 30 days from diagnosis.
  • Results showed that untreated patients had escalating mortality rates linked to biofilm levels, while treated patients with high biofilm formation had a significantly increased risk of death, even after controlling for other factors.
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The role of the type, stage and status of cancer in the outcome of COVID-19 remains unclear. Moreover, the characteristic pathological changes of severe COVID-19 reveled by laboratory and radiological findings are similar to those due to the development of cancer itself and antineoplastic therapies. To identify potential predictors of mortality of COVID-19 in cancer patients.

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Background: OXA-48-like carbapenemases have been found in a growing and varied number of carbapenemase-producing (CPE) isolates, and they are spreading to several countries. Although this oxacillinase leads to weak resistance to carbapenems without affecting broad-spectrum cephalosporin activity, when they are associated with other resistance mechanisms, the level of resistance to these antibiotics may be significantly higher. This weak resistance against carbapenems and cephalosporins, along with the absence of other resistance mechanisms, could render OXA-48-like harboring isolates undetected in the laboratory routine.

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