Publications by authors named "Freddy Sandi Lora"

Article Synopsis
  • A study looked at how a special treatment method called the CREVICE protocol helped patients with severe brain injuries do better after 6 months compared to not using a protocol at all.
  • They found that using CREVICE led to fewer deaths and better recovery scores for patients.
  • The research involved 501 patients mostly from public hospitals in South America and showed that having a structured protocol made a positive difference in their care.
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Background: Most patients with severe traumatic brain injury (sTBI) in low- or-middle-income countries and surprisingly many in high-income countries are managed without intracranial pressure (ICP) monitoring. The impact of the first published protocol (Imaging and Clinical Examination [ICE] protocol) is untested against nonprotocol management.

Objective: To determine whether patients treated in intensive care units (ICUs) using the ICE protocol have lower mortality and better neurobehavioral functioning than those treated in ICUs using no protocol.

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Article Synopsis
  • Intracranial pressure (ICP) monitoring for severe traumatic brain injury (sTBI) varies worldwide due to differences in resources and medical philosophies, with a lack of comprehensive management strategies for suspected intracranial hypertension (SICH) when monitoring is absent.
  • A consensus conference with 43 Latin American medical professionals refined the existing BEST:TRIP algorithm, creating the CREVICE (Consensus REVised ICE) algorithm to define SICH and outline management and treatment options.
  • The CREVICE algorithm serves as a structured decision-support model for sTBI management in settings without ICP monitoring, aiming to improve clinical care and guide future research, while being based on expert consensus due to limited existing literature.
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Background: Severe traumatic brain injury (sTBI) is a significant global health problem disproportionately affecting low- and middle-income countries (LMICs). Management of intracranial hypertension in sTBI is crucial to survival and optimal recovery. Practitioners in high-income countries routinely use intracranial pressure (ICP) monitors although their usefulness has been questioned.

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