Publications by authors named "Freddy Sandi"

Article Synopsis
  • The ICE algorithm is a unique method for treating traumatic brain injuries without using a specialized device for measuring intracranial pressure (ICP).
  • In a study involving 167 patients, the outcomes of those treated with the ICE method were similar to those who received standard monitored treatment, with a significant number surviving and showing improvement after 6 months.
  • Although the ICE protocol had a low rate of problems during treatment, its effectiveness might not be the same in other places due to different medical practices and conditions, so more research is needed.
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Purpose: To analyze the relationship between hypercapnia developing within the first 48 h after the start of mechanical ventilation and outcome in patients with acute respiratory distress syndrome (ARDS).

Patients And Methods: We performed a secondary analysis of three prospective non-interventional cohort studies focusing on ARDS patients from 927 intensive care units (ICUs) in 40 countries. These patients received mechanical ventilation for more than 12 h during 1-month periods in 1998, 2004, and 2010.

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Rationale: Baseline characteristics and management have changed over time in patients requiring mechanical ventilation; however, the impact of these changes on patient outcomes is unclear.

Objectives: To estimate whether mortality in mechanically ventilated patients has changed over time.

Methods: Prospective cohort studies conducted in 1998, 2004, and 2010, including patients receiving mechanical ventilation for more than 12 hours in a 1-month period, from 927 units in 40 countries.

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