Characterization of the Fungitoxic Activity on of -phenyl-driman-9-carboxamides.

A total of 12 compounds were synthesized from the natural sesquiterpene (-) drimenol (compounds 4 to 15). The synthesized compounds corresponded to -phenyl-driman-9-carboxamide derivatives, similar to some fungicides that inhibit the electron-transport chain. Their structures were characterized and confirmed by H NMR, C NMR spectroscopy, and mass spectrometry.

Inexpensive and green electrochemical sensor for the determination of Cd(II) and Pb(II) by square wave anodic stripping voltammetry in bivalve mollusks.

An inexpensive and environmental friendly electrochemical sensor based on a glassy carbon electrode (GC) modified with graphene quantum dots (GQDs) and Nafion (NF) has been developed for the determination of Cd(II) and Pb(II) in bivalve mollusks using square wave anodic stripping voltammetry (SWASV). GQDs were characterized by UV-Vis spectroscopy, fluorescence and transmission electronic microscopy (TEM). The modified electrode was evaluated by cyclic voltammetry, scanning electronic microscopy (SEM) and electrochemical impedance spectroscopy (EIS).

Electrical and Electrochemical Behavior of Carbon Paste Electrodes Modified with Ionic Liquids Based in -Octylpyridinium Bis(Trifluoromethylsulfonyl)Imide. A Theoretical and Experimental Study.

In this work, we studied carbon paste electrodes (CPEs) with two kinds of binders: mineral oil or ionic liquids (IL) derived from N-substituted octyl pyridinium bis(trifluoromethylsulfonyl)imide with the substituents H-, CH-, CN- and CF-. The work aims to study this series of IL and determine a possible effect of the substituent of the cation in the behavior of the IL as a binder of graphite for obtaining IL-CPEs. The electrochemical response and the electrical behavior were measured by cyclic voltammetry and electrochemical impedance spectroscopy, respectively.

Antifungal Activity against of 2,6-Dimethoxy-4-(phenylimino)cyclohexa-2,5-dienone Derivatives.

In this work the enzyme laccase from was used to synthetize 2,6-dimethoxy-4-(phenylimino)cyclohexa-2,5-dienone derivatives. Ten products with different substitutions in the aromatic ring were synthetized and characterized using ¹H- and C-NMR and mass spectrometry. The 3,5-dichlorinated compound showed highest antifungal activity against the phytopathogen , while the -methoxylated compound had the lowest activity; however, the antifungal activity of the products was higher than the activity of the substrates of the reactions.

Mitochondrial DNA Fitness Depends on Nuclear Genetic Background in .

Mitochondrial DNA (mtDNA) has been one of the most extensively studied molecules in ecological, evolutionary and clinical genetics. In its early application in evolutionary genetics, mtDNA was assumed to be a selectively neutral marker conferring negligible fitness consequences for its host. However, this dogma has been overturned in recent years due to now extensive evidence for non-neutral evolutionary dynamics.

Catalytic and regulatory roles of species involved in metal-nucleotide equilibriums in human pyridoxal kinase.

Pyridoxal 5'-phosphate is the active form of vitamin B6 and its deficiency is directly related with several human disorders, which make human pyridoxal kinase (hPLK) an important pharmacologic target. In spite of this, a carefully kinetic characterization of hPLK including the main species that regulates the enzymatic activity is at date missing. Here we analyse the catalytic and regulatory mechanisms of hPLK as a function of a precise determination of the species involved in metal-nucleotide equilibriums and describe new regulatory mechanisms for this enzyme.