Publications by authors named "Freddy Fernando Guebely De la Hoz"
Lancet Infect Dis
October 2024
Article Synopsis
- This study aimed to evaluate targeted next-generation sequencing (NGS) as a method for diagnosing drug-resistant tuberculosis by reviewing existing data on its effectiveness and prevalence in detecting mutations across different gene targets.
- The researchers conducted a systematic review and meta-analysis of various sources for publications related to targeted NGS from 2005 to 2022, focusing on studies that utilized the technique for drug resistance prediction in tuberculosis.
- They assessed the diagnostic accuracy of targeted NGS by analyzing sensitivity and specificity compared to traditional drug susceptibility testing methods, using a Bayesian model for comprehensive results.
