Electroencephalography (EEG) is a non-invasive method used to track human brain activity over time. The time-locked EEG to an external event is known as event-related potential (ERP). ERP can be a biomarker of human perception and other cognitive processes.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2018
The biomedical signal classification accuracy on motor imagery is not always satisfactory, partially because not all the important features have been effectively extracted. This paper proposes an improved dynamic feature extraction approach based on a time-frequency representation and an optimal sequence similarity measurement. Since the wavelet packet decomposition (WPD) generates more detailed signal variation information and the dynamic time warping (DTW) helps optimally measure the sequence similarity, more important features are kept for classification.
View Article and Find Full Text PDFAcad Emerg Med
April 2016
Objectives: Postconcussion symptoms (PCS) are a common complication of mild traumatic brain injury (TBI). Currently, there is no validated clinically available method to reliably predict at the time of injury who will subsequently develop PCS. The purpose of this study was to determine if PCS following mild TBI can be predicted during the initial presentation to an emergency department (ED) using a novel robotic-assisted assessment of neurologic function.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
December 2015
A study is conducted to determine the dimensions of an exhaled flow measuring mouthpiece for a breath-sampling device that requires breathing for an extended period of time. Fleisch, Pitot and Venturi type differential pressure based flow measuring mouthpieces of various dimensions are evaluated. Inner diameters (IDs) of the cylinder shaped Fleisch, Pitot and Venturi mouthpieces are varied from 5mm to 25mm.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
October 2015
Alveolar air Volatile Organic Compound (VOC) extractor is a handheld breath-sampling device for clinical breath analysis. The device consists two main components: (1) An alveolar air separator, (2) A VOC extractor. The alveolar air separator splits exhaled air based on total exhaled air volume directing alveolar air towards the VOC extractor and dead space air to into an exhaust channel.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
October 2015
Post-Concussion Syndrome (PCS) is a common sequelae of mild Traumatic Brain Injury (mTBI). Currently, there is no reliable test to determine which patients will develop PCS following an mTBI. As a result, clinicians are challenged to identify patients at high risk for subsequent PCS.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
November 2015
This paper presents a prototype of a programmable cerebrospinal fluid (CSF) external drainage system that can accurately measure the dispensed fluid volume. It is based on using a miniature spectrophotometer to collect color data to inform drain rate and pressure monitoring. The prototype was machined with 1 μm dimensional accuracy.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
June 2016
Wearable devices are arguably one of the most rapidly growing technologies in the computing and health care industry. These systems provide improved means of monitoring health status of humans in real-time. In order to cope with continuous sensing and transmission of biological and health status data, it is desirable to move towards energy autonomous systems that can charge batteries using passive, ambient energy.
View Article and Find Full Text PDFUnlabelled: The objective of this paper is to demonstrate the effective deployment of a robotic assessment tool for the evaluation of mild traumatic brain injury (mTBI) patients in a busy, resource-constrained, urban emergency department (ED).
Methods: Functional integration of new robotic technology for research in the ED presented several obstacles that required a multidisciplinary approach, including participation from electrical and computer engineers, emergency medicine clinicians, and clinical operations staff of the hospital. Our team addressed many challenges in deployment of this advanced technology including: 1) adapting the investigational device for the unique clinical environment; 2) acquisition and maintenance of appropriate testing space for point-of-care assessment; and 3) dedicated technical support and upkeep of the device.
Annu Int Conf IEEE Eng Med Biol Soc
August 2015
Many professions place significant mental and/or physical strain on their workers. Some professionals (such as firefighters, soldiers, and pilots) have an inherent responsibility for the safety of others. Making sure that workers in these remain fit for duty is an important health/safety concern for the workers and those they serve.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
August 2015
A design for a modular, compact, and accurate wireless electroencephalograph (EEG) system is proposed. EEG is the only non-invasive measure for neuronal function of the brain. Using a number of digital signal processing (DSP) techniques, this neuronal function can be acquired and processed into meaningful representations of brain activity.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2015
With 42,000 cases reported annually in the United States and an approximate 10% mortality rate, [1] pediatric septic shock is a major health problem that is often difficult to treat effectively. Several studies have shown that children experiencing pediatric septic shock often have critically low levels of serum zinc (Zn), suggesting supplementation of Zn to be an effective therapeutic strategy. However, to protect the safety and well-being of the patient, it is extremely important to monitor blood serum concentration of Zn during supplementation in order to ensure that levels remain at or near the physiological norm and thus minimize the risk of heavy metal toxicity from over supplementation.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2015
This paper presents a prototype of a wireless, point-of-care medical device to measure head impacts in contact or collision sports. The device is currently capable of measuring linear acceleration, time, and the duration of impact. The location of the impact can also be recorded by scaling the prototype design to multiple devices.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
June 2014
This paper presents prototypes of a hardware interface that is directed towards possible integration with a Point-of-Care Testing Environment for Neurological Assessment (POCTENA). While the complete system is intended to assist with diagnosis of mild Traumatic Brain Injury (TBI), the focus of this paper is to present designs of necessary hardware that can be used to assess upper-limb motor performance in a point-of-care setting. The hardware interface is expected to facilitate execution of several visuomotor tasks in an attempt to reliably quantify motor deficits.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
August 2013
In this paper, we present a prototype design of POCTENA (Point-Of-Care Testing Environment for Neurological Assessment), a medical computing system that will be used to assist with diagnosis of mild traumatic brain injury. The design includes an initial set of neurological tests that are built into the system. Component-based usability testing was conducted to examine the effectiveness of the user interface.
View Article and Find Full Text PDFMost entrepreneurial ventures fail long before the core technology can be brought to the marketplace because of disconnects in performance and usability measures such as accuracy, cost, complexity, assay stability, and time requirements between technology developers' specifications and needs of the end-users. By going through a clinical needs assessment (CNA) process, developers will gain vital information and a clear focus that will help minimize the risks associated with the development of new technologies available for use within the health care system. This article summarizes best practices of the principal investigators of the National Institute of Biomedical Imaging and Bioengineering point-of-care (POC) centers within the National Institute of Biomedical Imaging and Bioengineering POC Technologies Research Network.
View Article and Find Full Text PDFBackground: Neurologic emergencies are common, frequently devastating, and benefit from timely diagnosis and treatment. Point of care (POC) technologies have the potential to assist clinicians caring for these patients. In order to prioritize development of new POC testing, a thorough assessment of clinical needs is required.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2012
In the Unites States Pediatric septic shock is a major health problem with about 42,000 cases per y ear and a mortality rate of about 10% [1]. Studies have indicated that children with pediatric septic shock have demonstrated critically low levels of serum z inc (Zn) and supplementation of Zn is being suggested as a therapeutic strategy. However, to protect patient safety, it is vital that Z n levels be monitored during supplementation to insure the Zn concentration levels remain at or near physiologic normal levels.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
June 2012
Subarachnoid hemorrhage (SAH) is a dangerous neurological event with a very short time window for early diagnosis. Clinical diagnoses performed in a lab seek to quantify bilirubin in cerebrospinal fluid (CSF) as a biomarker for SAHs; however laboratory assays suffer from lengthy protocols, interference from hemoglobin, and the availability of expertise. Substantial improvements in the determination of bilirubin concentration in the presence of hemoglobin in CSF are demonstrated in this work.
View Article and Find Full Text PDFIn North America, an estimated 30,000 patients annually experience an aneurysmal subarachnoid hemorrhage (SAH). In approximately five percent of these patients, the hemorrhage is not visible on computerized tomography scans due to the inability to image blood at time intervals greater than 12 h post symptom onset. For these patients (many of which have experienced a sentinel hemorrhage that is a precursor to a more significant rupture), a method is needed for accurately analyzing cerebral spinal fluid (CSF) for evidence of SAH.
View Article and Find Full Text PDFThe increasingly global focus on health care issues continues to underline the importance of point-of-care technologies and their ability to provide cost-effective solutions that address many unmet health care needs. Further, the current crisis in health care costs has critically underscored the need for research and development into highly effective, but low cost means of delivering health care. With a focus on providing clinically actionable information at or near the patient, point-of-care devices provide clinicians with information that is critical to the management of patient care while they are still with the patient.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
March 2011
In North America, an estimated 30,000 patients annually experience an aneurysmal subarachnoid hemorrhage (SAH). In approximately five percent of these patients, the hemorrhage is not visible on computerized tomography scans due to the inability to image blood at time intervals greater than 12 hours post symptom onset. For these patients (many of which have experience a sentinel hemorrhage that is a precursor to a more significant rupture) a method is needed for accurately analyzing cerebral spinal fluid (CSF) for evidence of SAH.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
April 2011
Neonatal jaundice is a medical condition which occurs in newborns as a result of an imbalance between the production and elimination of bilirubin. Excess bilirubin in the blood stream diffuses into the surrounding tissue leading to a yellowing of the skin. An optical system integrated with a signal processing system is used as a platform to noninvasively quantify bilirubin concentration through the measurement of diffuse skin reflectance.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
March 2011
Steady state diffuse reflectance spectroscopy is a nondestructive method for obtaining biochemical and physiological information from skin tissue. In medical conditions such as neonatal jaundice excess bilirubin in the blood stream diffuses into the surrounding tissue leading to a yellowing of the skin. Diffuse reflectance measurement of the skin tissue can provide real time assessment of the progression of a disease or a medical condition.
View Article and Find Full Text PDFBackground: Neurological emergencies are common and frequently devastating. Every year, millions of Americans suffer an acute stroke, severe traumatic brain injury, subarachnoid hemorrhage, status epilepticus, or spinal cord injury severe enough to require medical intervention.
Aims: Full evaluation of the diseases in the acute setting often requires advanced diagnostics, and treatment frequently necessitates transfer to specialized centers.