Publications by authors named "Fred E Husserl"
Background & Objectives: Chronic kidney disease (CKD) is commonly complicated by secondary hyperparathyroidism (SHPT), leading to increased risk of morbidity and mortality. SHPT is a progressive disease often requiring long-term therapy to control parathyroid hormone (PTH) and mineral imbalances. Vitamin D sterols and phosphate binders, used as traditional therapies to lower PTH and phosphorus, may provide inadequate long-term control for many dialysis patients.
View Article and Find Full Text PDFImpact of multidisciplinary, early renal education on vascular access placement.
Nephrol News Issues
February 2005
Background: The Ochsner Clinic Foundation initiated the Healthy Start Clinic to identify, educate, and refer chronic kidney disease patients to nephrologists earlier in the course of their disease. This study investigated the impact of a structured educational session on the type and timing of permanent vascular access placement in patients receiving hemodialysis.
Methods: Before initiating dialysis, the HSC patient group received a general overview of the kidney and kidney disease, plus one-on-one instruction from a registered nurse, a dietitian, and a social worker.
Article Synopsis
- Management of secondary hyperparathyroidism is difficult with traditional treatments, but the calcimimetic cinacalcet HCl improves sensitivity to calcium and lowers parathyroid hormone (PTH) levels.
- A phase 3 study involving 395 hemodialysis (HD) and peritoneal dialysis (PD) patients showed that cinacalcet was significantly more effective than a placebo in reducing PTH levels, with notable improvements in the proportion of patients who achieved target iPTH levels.
- Cinacalcet also reduced serum calcium and phosphorus levels, with mild side effects, presenting it as a promising new option for managing secondary hyperparathyroidism in dialysis patients.