Designed and synthesized novel tripeptides targeting diabetes and its related pathologies.

In diabetes and its associated pathologies, glycation, α-amylase, and α-glucosidase play crucial roles. This study introduces a novel tripeptide, RWW, designed to target glycation and key enzymes in diabetes management. Using in silico methods, RWW was optimized to interact with the glycation-prone Human serum albumin (HSA) sites, as well as inhibit α-amylase and α-glucosidase.

Synergistic efficacy of ZnO quantum dots, Ag NPs, and nitazoxanide composite against multidrug-resistant human pathogens as new trend of revolutionizing antimicrobial treatment.

Antibiotic resistance is currently becoming a more serious threat to global health, especially in severe nosocomial infections treatment by multidrug-resistant bacteria. This research provides a new way of synergizing green-synthesis for zinc oxide quantum dots (ZnO-QDs with hexagonal crystals) that are 7 nm in diameter and zero-valent Ag cubic crystals that are 67 nm in size embedded with nitazoxanide substrate (NAZ). Instrumental characterization like SEM, TEM, EDAX, and FT-IR and comprehensive antimicrobial studies were conducted to study the incorporation behavior of composites based on Ag NPs/ZnO QDs/NAZ.

analysis to identify potential antitubercular molecules in through virtual screening and molecular dynamics simulations.

A major obstacle in the treatment of tuberculosis (TB) is to combat the emerging resistant strains of its causing agent i.e. (MTb).

Association between different behavioral factors and dental caries among children attending the dental clinics in a sample from Saudi Arabia.

Background: This study aimed to assess the association between different behavioral factors and the prevalence of dental caries among children attending the dental clinic in a sample from the Hail and Tabuk regions, Saudi Arabia.

Method: A cross-sectional study design was employed to determine the burden of dental caries in teeth and key associated factors among 6-12-year-old children who attended different dental clinics. The data was recruited from Hail and Tabuk districts, Saudi Arabia.

Prevalence and Risk Factors of Dental Trauma in Ha'il, Saudi Arabia.

Aim: This study will aid in determining the prevalence and risk factors for dental trauma. This will assist in developing a treatment budget plan, thereby, fend off complications.

Materials And Methods: This study was an observational study, having a cross-sectional design, in which information was obtained from 555 participants.

Gut microbiome interactions with graphene based nanomaterials: Challenges and opportunities.

Rapid growth of nanotechnology has accelerated immense possibility of engineered nanomaterials (ENMs) exposure by human and living organisms. In this context, wide range applications of graphene based nanomaterials (GBNMs) may inevitably cause their release into the environment. Consequently, potential risks to the ecological system and human health is consistently increasing due to the probable ingestion of GBNMs by mean of contaminated water or food sources.

Level of anxiety and depression among undergraduate dental students of University of Hail, Saudi Arabia.

Background: Dental students have been identified as having a high level of stress.

Objective: This study aimed to assess the prevalence of anxiety and depression among undergraduate dental students of university of Hail and to determine the association of anxiety and depression in terms of gender and respective year of study.

Methods: This was an observational cross-sectional study.

Prevalence of dental caries in Pakistan: a systematic review and meta-analysis.

Background: Optimum oral health is impossible to achieve without managing dental caries. The first step to manage dental caries at a community level is to know its prevalence and trend. Unfortunately, the prevalence of dental caries at the national/regional level is not known in many developing countries.

Effect of Nd:YAG, Er,Cr:YSGG Laser Irradiation, and Adjunctive Photodynamic Therapy on Push-Out Bond Strength of Zirconia Posts to Radicular Dentin.

This study is aimed at assessing the influence of Nd:YAG, Er,Cr:YSGG laser irradiation, and adjunctive photodynamic therapy (aPDT) on the bond strength of zirconia posts to radicular dentin. Eighty extracted anterior teeth were randomly categorized into 4 groups ( = 20) based on varying laser irradiation treatments, i.e.

Perceptions towards Use of Electronic Dental Record at a Dental College, University of Hail, Kingdom of Saudi Arabia.

Aim: This study highlights the use of electronic dental record (EDR) of a dental college at the University of Hail. This study has examined the perceptions of the stakeholders in regard to the objective mentioned above.

Materials And Methods: It was a cross-sectional survey.

Tobacco Smoke Carcinogens Induce DNA Repair Machinery Function Loss: Protection by Carbon Nanotubes.

Purpose: DNA damage is a continuous process occurring within the cells caused by intrinsic and extrinsic factors, but it gets repaired regularly. If the DNA repair process is faulty, the incidences of damages/mutations can accumulate in cells resulting in cell transformation. It is hypothesized that the negative variations in DNA repair pathways in even at one point viz.

Knowledge and practice regarding prevention of COVID-19 among the Saudi Arabian population.

Background: Prevention is the best way to manage a pandemic like COVID-19. The World Health Organization has issued public advice to create awareness by providing people knowledge to prevent/protect them from COVID-19. Hence, the present study was planned to assess knowledge of prevention and its practical use amongst samples from the Saudi Arabian population.

Prevention Knowledge and Its Practice Towards COVID-19 Among General Population of Saudi Arabia: A Gender-based Perspective.

Background: This study is an original contribution to the gender-based perspective of measuring knowledge and practice towards COVID-19 among the Saudi population.

Objective: This study investigates the existing knowledge of COVID-19 among both genders and its likely use in practice to combat COVID-19.

Design And Setting: Cross-sectional study with an online survey and data collected from all the five regions of Saudi Arabia.

Measurement of Parents' Knowledge toward Oral Health of their Children: An Observational Study from Hail, Saudi Arabia.

Aim: Parents' knowledge of oral health maintenance is of crucial importance. Children are dependent on their parents for the maintenance of their oral health. Hence, the present study is aimed to measure parents' knowledge toward the oral health of their children.

Alveolar Osteitis: Patient's Compliance with Post-extraction Instructions Following Permanent Teeth Extraction.

Aim: The study aims to evaluate the patients' compliance with post-extraction instructions to prevent the development of alveolar osteitis and keep the health of the socket. Alveolar osteitis "Dry socket" is considered one of the most common complications after extraction.

Materials And Methods: Study was based on an observational cross-sectional design involving 201 subjects (individuals).