Therapeutic relationships in speech-language pathology: A scoping review of empirical studies.

Purpose: This scoping review provides an overview of empirical studies investigating therapeutic relationships between speech-language pathologists (SLPs), clients, and caregivers across all ages and clinical areas, and identifies areas of future research.

Method: The Joanna Briggs Institute's (JBI) scoping review method was employed. Systematic searches were conducted across seven databases and four grey literature databases.

Therapeutic relationships in speech-language pathology: a scoping review protocol.

Objective: The purpose of this scoping review is to provide an overview of empirical research regarding the therapeutic relationship between speech-language pathologists and their clients of all ages and clinical areas.

Introduction: The influence of a positive relationship between professionals and clients on the process and outcome of interventions is well documented for many health professions. However, research in speech-language pathology predominantly focuses on the outcome of specific treatment methods and techniques.

Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex.

In yeast, the membrane-bound HMG-CoA reductase degradation (HRD) ubiquitin-ligase complex is a key player of the ER-associated protein degradation pathway that targets misfolded proteins for proteolysis. Yos9, a component of the luminal submodule of the ligase, scans proteins for specific oligosaccharide modifications, which constitute a critical determinant of the degradation signal. Here, we report the crystal structure of the Yos9 domain that was previously suggested to confer binding to Hrd3, another component of the HRD complex.