Publications by authors named "Franziska Wojciech"
Proc Natl Acad Sci U S A
September 2015
Article Synopsis
- Researchers studied the role of long noncoding RNAs (lncRNAs) in regulating the transcription factor MYC, which is known to influence cancer development, focusing on B-cell lymphomas.
- They identified a specific lncRNA, named MYC-induced long noncoding RNA (MINCR), that shows a strong correlation with MYC and is differentially expressed in Burkitt lymphoma.
- Knocking down MINCR impaired cell cycle progression and reduced MYC binding to genes related to cell cycle regulation, suggesting that MINCR plays a critical role in the MYC transcriptional network and may affect cancer cell proliferation.
