Publications by authors named "Franziska Leidreiter"
Article Synopsis
- * Despite being important for nitrogen cycling, the structure of NXR was not well understood until this study, which utilized advanced imaging techniques and biochemistry to analyze the NXR from the bacterium Kuenenia stuttgartiensis.
- * The findings reveal that NXR not only oxidizes nitrite but also reduces nitrate, with a unique tubule formation influenced by a new haem-containing subunit, and they provide insights into the enzyme's active site and electron transfer
Toxin complex (Tc) toxins are virulence factors of pathogenic bacteria. Tcs are composed of three subunits: TcA, TcB and TcC. TcA facilitates receptor-toxin interaction and membrane permeation, TcB and TcC form a toxin-encapsulating cocoon.
View Article and Find Full Text PDFTc toxins from pathogenic bacteria use a special syringe-like mechanism to perforate the host cell membrane and inject a deadly enzyme into the host cytosol. The molecular mechanism of this unusual injection system is poorly understood. Using electron cryomicroscopy, we determined the structure of TcdA1 from Photorhabdus luminescens embedded in lipid nanodiscs.
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