Clinical Course, Genetic, and Immunohistochemical Characterization of Solid Pseudopapillary Tumor of the Pancreas (Frantz Tumors) in a Brazilian Cohort.

Frantz tumors or solid pseudopapillary pancreatic neoplasm (SPN) are rare exocrine neoplasms that carry a favorable prognosis; they represent up to 3% of all tumors located in the region of the pancreas and have specific age and gender predispositions. In recent years, the rising curve of diagnosis is entitled to the evolution and access of diagnostic imaging. In this paper, we have retrospectively reviewed and described the clinical course of 40 patients with SPN from three institutions in Brazil, who had their diagnosis between 2005 and 2020, and analyzed the clinicopathological, genetic, and surgical aspects of these individuals.

Abdominal drain amylase on the first day after pancreatectomy: a predictive factor for pancreatic fistula.

Objective: To analyze abdominal drain on the first postoperative day and evaluate its predictive nature for the diagnosis of Pancreatic Fistula exclusion, seeking to establish a cutoff point from which lower values demonstrate safety in excluding the possibility of this complication.

Methods: From August 2017 to June 2020, data from 48 patients undergoing pancreatic resection were collected and analyzed from a prospective cohort. The patients were divided into two groups, one group consisting of patients who did not develop PF (Group A), and the other composed of patients who developed PF (Group B).

A rare non-oncological pancreatic mass: eosinophilic pancreatitis diagnosis through EUS-FNA.

Eosinophilic pancreatitis (EP) is a rare etiology of chronic pancreatitis, and few cases have been reported. It is characterized by eosinophilic infiltration of the pancreas and elevated IgE levels. EP is difficult to distinguish from pancreatic cancer based on clinical symptoms and auxiliary exams.

SOLID PSEUDOPAPILLARY NEOPLASM OF THE PANCREAS.

Background: The solid pseudopapillary neoplasm is a rare tumor of the pancreas. However, it´s etiology still maintain discussions.

Aim: To analyze it´s clinical data, diagnosis and treatment.

Diffusion-weighted magnetic resonance imaging indicates the severity of acute pancreatitis.

Purpose: To test the use of diffusion-weighted magnetic resonance imaging (DW-MRI) to differentiate between different degrees of severity of acute pancreatitis (AP).

Method: Thirty-six patients who underwent DW-MRI and magnetic resonance cholangiopancreatography were divided into patients with mild AP (mAP, n = 15), patients with necrotizing AP (nAP, n = 8), and patients with a normal pancreas (nP, n = 15; controls). The pancreas was divided into head, body, and tail, and each segment was classified according to image features: pattern 1, normal; pattern 2, mild inflammation; and pattern 3, necrosis.

Ethyl-pyruvate reduces lung injury matrix metalloproteinases and cytokines and improves survival in experimental model of severe acute pancreatitis.

Purpose: To investigate if the ethyl-pyruvate solution could reduce mortality in AP and/or diminish the acute lung injury.

Methods: Forty male rats, weighing between 270 to 330 grams were operated. An experimental model of severe AP by injection of 0.

Severe acute pancreatitis: results of treatment.

Objective: To evaluate the results of the Protocol for treatment of patients with severe acute pancreatitis.

Methods: We consecutively analyzed age, gender, etiology, length of hospital stay, type of treatment and mortality of 37 patients with severe acute pancreatitis from January 2002.

Results: The patients' ages ranged from 20 to 88 years (average 50 years), 27% were female and 73% male.

Castleman's disease mimetizing pancreatic tumor.

Context: Angiofollicular lymph node hyperplasia or Castleman's disease is a rare clinical condition. Knowledge about etiology and physiopathology; and treatment management as well are yet to be defined. Unicentric presentation of this disease affecting single lymph nodes in the mediastinum seems to be the most common presentation.

Expression of p53, p16 and Ki67 proteins in ductal adenocarcinoma of the pancreatic head and their relation with survival and cell differentiation.

Objective: To determine the expression of p53, p16 and Ki-67 and its relevance in survival and cell differentiation.

Methods: Fifteen duodenopancreatectomized patients were included. Immunohistochemical expression of p53, p16 and Ki-67 was determined in paraffin embedded tumor blocks.

[Pancreatic insulinomas: diagnosis and treatment].

Background: Despite its rarity, the insulinoma is the most common pancreatic neuroendocrine tumor.

Objective: Analyze clinical and immunohistochemical data from surgical resection of the pancreas insulinoma.

Method: Twelve cases are described, concerning surgical aspects, complications and medium-long term outcome of patients.