Publications by authors named "Franz Loeffler"

Background: Infective endocarditis (IE) requires multidisciplinary management. We established an endocarditis team within our hospital in 2011 and a state-wide endocarditis network with referring hospitals in 2015. We aimed to investigate their impact on perioperative outcomes.

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  • Cortical characteristics like thickness, surface area, and volume change with age, cognitive function, and various neurological and psychiatric disorders.
  • A study of 22,824 individuals from multiple cohorts evaluated genetic factors influencing these brain measures, identifying 160 significant genetic associations linked to specific biological pathways.
  • Findings suggest a genetic connection between cortical traits and factors related to physical development, brain health, and mental illnesses, providing valuable insights for future research on brain changes with aging.
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  • * Two principal components were identified: PC1 which captures global variations in surface area across most cortical regions, and PC2 specifically associated with visual regions.
  • * We found that genetic loci linked to PC1 correlate with general cognitive functions, while those linked to PC2 are related to visual aptitudes, indicating that variations in brain structure may influence occupational choices.
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Background: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is an attractive alternative to systemic therapy based on low minimum inhibitory concentrations (MICs, commonly <0.03 mg/l) documented in canine pathogenic staphylococci, including strains of MRSA and MRSP (methicillin-resistant Staphylococcus aureus and S.

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