Aim: This study aimed to evaluate the healing of peri-implant defects grafted with microparticles (MPs).
Material And Methods: Six domestic pigs received nine standardized defects at the calvaria, and an implant was inserted in the middle of each defect. The space between the implant and lateral bone portion was filled with MP pellets (n = 18) or MP supernatant (n = 18) or left unfilled (n = 18).