Publications by authors named "Franz G Poch"
Background: Vascular cooling effects are a well-known source for tumor recurrence in thermal in situ ablation techniques for hepatic malignancies. Microwave ablation (MWA) is an ablation technique to be considered in the treatment of malignant liver tumors. The impact of vascular cooling in MWA is still controversial.
View Article and Find Full Text PDFContrast-enhanced computed tomography (CECT) is used to monitor technical success immediately after hepatic microwave ablation (MWA). However, it remains unclear, if CECT shows the exact extend of the thermal destruction zone, or if tissue changes such as peri-lesionary edema are depicted as well. The objective of this study was to correlate immediate post-interventional CECT with histological and macroscopic findings in hepatic MWA in porcine liver .
View Article and Find Full Text PDFArticle Synopsis
- Ongoing research aims to improve the safety of radiofrequency ablation (RFA) for liver tumors using animal models, focusing on understanding the accuracy of ablation zone observations.
- The study involved performing RFA on domestic pigs' livers and analyzing the results through both photography and histological techniques, measuring cell viability in the resulting ablation zones.
- Findings revealed three distinct ablation zones with strong correlations between macro and micro-morphological data, demonstrating the ability to differentiate between non-viable (white zone) and various viable cell areas (red zones) in the liver tissue after RFA.
Article Synopsis
- The study aimed to assess vascular cooling effects in multipolar radiofrequency ablation (RFA) compared to conventional methods, particularly focusing on their impact on ablation shapes and areas.
- Multipolar RFA was tested ex vivo using porcine liver, and various configurations of applicators were employed alongside a simulated vessel to evaluate cooling effects.
- Results indicated that while cooling effects were observed around perfused vessels, they did not significantly alter the overall ablation area, but did affect the shape of the ablation zone.
Minimal vascular flows cause strong heat sink effects in hepatic radiofrequency ablation ex vivo.
J Hepatobiliary Pancreat Sci
August 2016
Article Synopsis
- The study evaluates how low vascular flow rates affect cooling in bipolar radiofrequency ablation (RFA) in pig liver samples.
- Flow rates as low as 1 ml/min created a noticeable cooling effect, with the maximum impact observed at 10 ml/min.
- It suggests that even minimal blood flow can hinder RFA effectiveness, highlighting the need for precautions when performing RFA near liver blood vessels.