Reduced Timing Variability in Patients with Unilateral Cerebellar Lesions during Bimanual Movements.

Timing variability on a repetitive tapping task was studied in subjects with unilateral cerebellar lesions. During unimanual tapping, within-hand variability was larger when tapping with the ipsilesional hand in comparison to tapping with the contralesional hand. However, variability in the impaired hand was greatly reduced when subjects tapped with two hands together.

Markers' influence on the duration discrimination of intermodal intervals.

The effects of sensory signal characteristics on the duration discrimination of intermodal intervals was investigated in three experiments. Temporal intervals were marked by either the successive presentation of a visual then auditory signal (VA), or by the successive presentation of an auditory then visual signal (AV). The results indicated that (1) VA intervals are generally easier to discriminate than are AV intervals, but this effect depends on the range of duration studied; (2) AV intervals are perceived as longer than VA intervals for durations ranging from 250 to 750 msec; (3) the intensity of the visual markers for both AV and VA intervals does not affect the discrimination; and (4) the perceived duration of an intermodal interval is influenced by the length of the first and second markers.

Motor Performance of Stutterers and Nonstutterers on Timing and Force Control Tasks.

Recently it has been suggested that speech and manual timing tasks share a common central process (Franz, Zelaznik, & Smith, 1992): Because stuttering is thought to be related to deficits in motoric processes such as timing, stutterers (n = 15) were compared with a set of age-, education-, and sex-matched nonstutterers on timing and isometric force-production tasks. In the timing tasks, subjects flexed and extended the right index finger at the metacarpophalangeal joint at cycle durations of 600, 500, 400, 300, and 200 ms. In the force-production tasks, subjects generated isometric forces to match target force levels displayed on a cathode-ray tube (CRT) screen.

Ranitidine in the treatment of non-ulcer dyspepsia. A placebo-controlled study in the Federal Republic of Germany.

The trial randomly assigned 652 patients with non-ulcer dyspepsia (NUD), defined as chronic or recurrent complaints of acid-related (heartburn, acid regurgitation, epigastric pain) and non-acid related (fullness/vomiting, nausea) symptoms and with no evidence of organic disease, to treatment for 4 weeks with 150 mg of ranitidine (Zantic, CAS 66357-59-3) twice a day, or placebo, according to a double-blind design. The presence and duration of all dyspeptic symptoms were recorded by interviews at the beginning and after 2 and 4 weeks of treatment as well as by diaries. The complete disappearance of all dyspeptic symptoms after 4 weeks in the placebo group was 36%; ranitidine treatment resulted in a significant improvement after 4 weeks (p < 0.

Evidence of Common Timing Processes in the Control of Manual, Orofacial, and Speech Movements.

Recent investigations of timing in motor control have been interpreted as support for the concept of brain modularity. According to this concept, the brain is organized into functional modules that contain mechanisms responsible for general processes. Keele and colleagues (Keele & Hawkins, 1982; Keele & Ivry, 1987; Keele, Ivry, & Pokorny, 1987; Keele, Pokorny, Corcos, & Ivry, 1985) demonstrated that the within-subject variability in.

[Treatment of acid-related diseases of the gastrointestinal tract. Observations in patients receiving a single evening dose of 300 mg ranitidine].

Unlabelled: Testing of the effectiveness and tolerability of ranitidine treatment in acid-related diseases of the gastrointestinal tract in non-selected outpatients.

Study Design: Observations made by 15,180 general practitioners and internists in the Länder of former West Germany in the period January 1989 to December 1990.

Patients: 23,783 patients with acid-related diseases of the gastrointestinal tract for which treatment with ranitidine is indicated (no further diagnostic or therapeutic requirement).

Spatial topological constraints in a bimanual task.

Previous research has shown that the concurrent performance of two manual tasks results in a tight temporal coupling of the limbs. The intent of the present experiment was to investigate whether a similar coupling exists in the spatial domain. Subjects produced continuous drawing of circles and lines, one task at a time or bimanually, for a 20 s trial.

Lupine influence on soil carbon, nitrogen and microbial activity in developing ecosystems at Mount St. Helens.

Lupine influence on soil C, N, and microbial activity was estimated by comparing root-zone soil (LR) to nonroot-zone soil (NR) collected at Mount St. Helens. Samples were collected from 5 sites forming a gradient of C and N levels as a reflection of different locations and varying volcanic disturbance by the 1980 eruption.

Size class structure and tree dispersion patterns in old-growth cedar-hemlock forests of the northern Rocky Mountains (USA).

Tree population size structures and dispersion patterns were studied using stem maps in three old-growth western hemlock (Tsuga heterophylla Sarg.)-western redcedar (Thuja plicata Donn.) stands in the Rocky Mountains of northern Idaho and adjacent Washington.

[Red pigment dyes and acne. Clinical observations and experimental investigations (author's transl)].

Acne-like changes were observed on a child's cheeks after colouring them with a red felt-tip pen. Numerous comedos appeared around a red tattoo coloured with felt-tip pen ink on a 16 year old girl. In animal experiments using rabbits' ears, two organic pigment inks found in these types of felt-tip pens could be proved to be the cause of a comedo-producing reaction.

[The histodynamic of alopecia areata in the dependence on the griseofulvin-induced epithelial proliferation (author's transl)].

The histodynamic of the alopecia areata--without or with the medicamentous induction of the hair growth respectively--was investigated comparatively. 1. Griseofulvin induced an epithelial proliferation in alopecia areata, which is noticeable in the surface epithelium as well as in the follicular epithelium.

[About the regression of psoriasis capitis after mechanical epilation (relations between the psoriatic efflorescence and the follicular proliferation) (author's transl)].

The pathomorphological and pathophysiological reactions of the spontaneous and artificially induced skincycle in psoriasis capitis-lesions were clinically and histologically investigated. 1. After the epilation in the psoriasis capitis-lesion a healing of the psoriatic efflorescence was observed.

[Oxygen consumption of the spontaneous and artificially induced skincycle at different times of day (author's transl)].

In the "clean" rat skin purified from the panniculus carnosus the oxygen consumption of the spontaneous and artificially induced skincycle was measured at different times of day. The level of oxygen consumption correlated to diurnal and nocturnal periods. During the skincycle the oxygen consumption showed fluctuations.

[Skincycle of a new spontaneous mutant (Nackig) with abnormal hair keratinization in the mouse (author's transl)].

The pathomorphological and pathophysiological reactions of the first skincycle of the mutant (Ng) were histologically investigated. 1. During the hair growth disturbances as the result of imperfect keratinisation changes of the morphology and function of different skin areas could be observed.

The effectiveness of topical antibacterials in acne: a double-blind clinical study.

In a double-blind study, three groups of patients with mild to moderate acne were treated for eight weeks with topical acne creams containing the antibacterials triclosan or triclosan plus propylene phenoxetol. The formula without antibacterials served as the control. Total-face lesion counts, evaluation of the overall degree of inflammation of the lesions, and patient self-assessment showed the added efficacy of the antibacterials when incorporated into the control.

[Effect of pregnancy and lactation on hair growth in mice (author's transl)].

The influence of pregnancy and suckling in mice on spontaneous, induced hair growth and on body weight was examined. 1. An inhibition of spontaneous and induced growth of hair some days before delivery was found.