Publications by authors named "Fransis Ghandour"
Article Synopsis
- Vascular complications in Type 2 diabetes mellitus (T2DM) lead to higher rates of illness and death, with a complex relationship in tissue angiogenesis known as the "angiogenic paradox."
- A study examined how macrovascular (EaHy926) and microvascular (HMEC-1) endothelial cells respond to high glucose and found that both types secreted pro-angiogenic factors, but the differences between them do not clarify the paradox.
- Metformin, a common diabetes medication, was shown to inhibit harmful factor secretion in high glucose conditions, suggesting that focusing on the factor EMMPRIN might be a promising strategy for managing vascular issues in diabetes.
Aims: It is commonly believed that pulmonary regurgitation (PR) after surgical repair of tetralogy of Fallot (TOF) leads to progressive right ventricular (RV) enlargement. However, progressive RV dilatation has never clearly been documented in this patient population. Therefore, we studied the size of the RV over time in patients after surgical TOF repair.
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