This is a presentation of a common symptom, acute chest pain, with a rare etiology and the relevant implications of spontaneous coronary artery dissection (SCAD) and fibromuscular dysplasia (FMD). In a tertiary hospital in South Florida, during the fall of 2023, an adult female patient with acute chest pain was admitted to the internal medicine ward. The ECG demonstrated no acute ischemic changes.
View Article and Find Full Text PDFBackground: Dystrophic epidermolysis bullosa is a rare genetic blistering skin disease caused by mutations in , which encodes type VII collagen (C7). Beremagene geperpavec (B-VEC) is a topical investigational herpes simplex virus type 1 (HSV-1)-based gene therapy designed to restore C7 protein by delivering .
Methods: We conducted a phase 3, double-blind, intrapatient randomized, placebo-controlled trial involving patients 6 months of age or older with genetically confirmed dystrophic epidermolysis bullosa.