Duodenal ulcer perforation: A systematic literature review and narrative description of surgical techniques used to treat large duodenal defects.

Background: There is no consensus on optimal surgical treatment of large duodenal defects arising from perforated ulcers, even though such defects are challenging to repair and inadequate repair is associated with high morbidity and mortality. The aim of this study was to carry out a systematic literature review of different surgical techniques used to treat large duodenal perforations, provide a narrative description of these techniques, and propose a framework for approaching this pathology.

Methods: PubMed/MEDLINE database was searched for articles published in English between January 1, 1970, and December 1, 2020.