Photoablation of Human Vitreous Opacities by Light-Induced Vapor Nanobubbles.

Myopia, diabetes, and aging are the main causes of progressive vitreous collagen aggregation, resulting in vitreous opacities, which can significantly disturb vision. As vitreous opacities, which induce the visual phenomenon of "floaters", are accessible with nanomaterials and light, we propose a nanotechnology-based approach to locally ablate them with highly reduced light energy compared to the more traditional YAG laser therapy. Our strategy relies on the plasmon properties of gold nanoparticles that generate vapor nanobubbles upon pulsed-laser illumination whose mechanical force can ablate vitreous opacities.

Paradoxical improvement of visual acuity in macular disease.

Purpose: Improvement in visual acuity is often considered the best indicator of the effectiveness of a treatment in age-related maculopathy. However, during the course of the disease, the location of the patients' preferred retinal locus of fixation may change. This can lead to an unexpected functional improvement, unrelated to treatment.

Combined use of SLO microperimetry and OCT for retinal functional and structural testing.

Background: This study compared SLO microperimetry scotoma size measurements with the sizes of lesions assessed with OCT in the areas of scotoma.

Methods: SLO microperimetry was performed on eight patients to assess the location and extent of scotoma areas. An SLO microperimetry master image was used to localize the scotoma areas in the real time OCT fundus image and to center OCT cross scans on the areas of scotoma.

Scanning eye movements in homonymous hemianopia documented by scanning laser ophthalmoscope retinal perimetry.

Sparing or partial recovery of visual fields in hemianopic patients is frequently difficult to document. This is because when testing large field losses, the standard automated or manual visual field testing systems have limited fixation controls. Measured visual field recovery in these cases may not be real but instead may be due to an artifact such as scanning eye movement.