Inhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progression.

Background: IL-19 is expressed in esophageal squamous cell carcinoma (SCC), but its biological effect on esophageal cancer remains unclear. We determined the correlation between IL-19 expression levels and clinicopathological variables and explored the effects of IL-19 on the esophageal SCC in vivo and in vitro.

Methodology/principal Findings: We determined the expression levels of esophageal SCC tissues from 60 patients using immunohistochemistry.