Publications by authors named "Franklin Romulo Aguilar-Gamboa"
Article Synopsis
- Monkeypox, a viral disease primarily found in West and Central Africa, has seen a significant increase in cases globally over the last decade, particularly during a multinational outbreak in 2022, suggesting possible evolutionary changes in the virus.
- A review of 271 articles published during the outbreak period identified 49 relevant studies that highlight challenges related to waning immunity, altered transmission routes, and genomic changes in the virus, complicating containment efforts.
- The findings suggest that Monkeypox may be filling an ecological niche previously occupied by smallpox, with specific genetic mutations being linked to its recent epidemiological changes and the need for continued surveillance and vaccination to control future outbreaks.
Introduction: Transplacental infections are frequent, especially in developing countries, where limited screening is performed to find infectious agents in the pregnant population. We aim to determine the clinical and epidemiological characteristics and seroinfection of antibodies against , parvovirus B19, , and HIV in pregnant women who attended the Motupe Health Center in Lambayeque, Peru during July-August 2018.
Methods: A descriptive cross-sectional study was conducted in 179 pregnant women interviewed with a standardized questionnaire.
Genomic and Phylogenetic Characterisation of SARS-CoV-2 Genomes Isolated in Patients from Lambayeque Region, Peru.
Trop Med Infect Dis
February 2024
Objective: this study aims to identify and characterise genomic and phylogenetically isolated SARS-CoV-2 viral isolates in patients from Lambayeque, Peru.
Methods: Nasopharyngeal swabs were taken from patients from the Almanzor Aguinaga Asenjo Hospital, Chiclayo, Lambayeque, Peru, which had been considered mild, moderate, and severe cases of COVID-19. Patients had to have tested positive for COVID-19, using a positive RT-PCR for SARS-CoV-2.
SARS-CoV-2 has spread widely throughout the world, and multiple mutations and variants of interest were detected in the late 2020 and continue to emerge. Although genetic diversity is common in RNA viruses, these variations at the genetic level have given it certain characteristics associated with transmission, resistance to neutralizing antibodies, and even suspected increased lethality. Better understanding of the genomic diversity in SARS-CoV-2 will help to take appropriate containment measures against the virus.
View Article and Find Full Text PDFHere, we report the genomic sequences of five severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains obtained from nasopharyngeal samples from five tested coronavirus disease 2019 (COVID-19)-infected patients from the Lambayeque region in Peru during early April 2020.
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