Publications by authors named "Franklin A"

Nurse leaders must utilize diverse operational skills in today's healthcare delivery system. Thus, the purposes of this article are to describe 1 institution's experience in expanding the role of a nonclinical house administrator to a nurse-led Hospital Operations Administrator team. The skills reflective of the American Organization of Nurse Executives competencies needed to successfully implement the newly configured role are discussed.

View Article and Find Full Text PDF

Building high-quality annotated clinical corpora is necessary for developing statistical Natural Language Processing (NLP) models to unlock information embedded in clinical text, but it is also time consuming and expensive. Consequently, it important to identify factors that may affect annotation time, such as syntactic complexity of the text- to-be-annotated and the vagaries of individual user behavior. However, limited work has been done to understand annotation of clinical text.

View Article and Find Full Text PDF

Decades of research has established that humans have preferences for some colors (e.g., blue) and a dislike of others (e.

View Article and Find Full Text PDF

Chimpanzees demand specialized housing and care and the highest degree of attention to animal welfare. The current project used a survey method to collate information on chimpanzee housing and behavioral indices of welfare across all 6 of the chimpanzee research facilities in the United States. Data were compiled on 701 chimpanzees ranging from 2 to 62 y old (mean age, 26.

View Article and Find Full Text PDF

Rotator cuff (RTC) repair outcomes are unsatisfactory due to the poor healing capacity of the tendon bone interface (TBI). In our preceding study, tendon hydrogel (tHG), which is a type I collagen rich gel derived from human tendons, improved biomechanical properties of the TBI in a rat chronic RTC injury model. Here we investigated whether adipose-derived stem cell (ASC)-seeded tHG injection at the repair site would further improve RTC healing.

View Article and Find Full Text PDF

Thousands of reports have demonstrated the exceptional performance of sensors based on carbon nanotube (CNT) transistors, with promises of transformative impact. Yet, the effect of long-term bias stress on individual CNTs, critical for most sensing applications, has remained uncertain. Here, we report bias ranges under which CNT transistors can operate continuously for months or more without degradation.

View Article and Find Full Text PDF

During animal contests over resources, opponents often signal their fighting ability in an attempt to avoid escalating to physical attack. A reliable signal is beneficial to receivers because it allows them to avoid injuries from engaging in contests they are unlikely to win. However, a signaler could benefit from deceiving an opponent by signaling greater fighting ability or greater aggressive intent than the signaler possesses.

View Article and Find Full Text PDF

Purpose: Poor healing of the tendon-bone interface (TBI) after rotator cuff (RTC) tears leads to high rates of recurrent tear following repair. Previously, we demonstrated that an injectable, thermoresponsive, type I collagen-rich, decellularized human tendon-derived hydrogel (tHG) improved healing in an acute rat Achilles tendon injury model. The purpose of this study was to investigate whether tHG enhances the biomechanical properties of the regenerated TBI in a rat model of chronic RTC injury and repair.

View Article and Find Full Text PDF
Article Synopsis
  • Acoustic patterning with ultrasound standing waves offers a promising biotechnology for creating organized cell systems, useful for developing organoid cultures and complex tissues.
  • However, challenges like cell array uniformity and disruption factors remain, with no thorough assessment of acoustically-patterned cell quality conducted until now.
  • This study introduces Voronoï tessellation to create metrics for evaluating the impact of various parameters on cell patterns, aiming to enhance quality control and process tracking in acoustic patterning.
View Article and Find Full Text PDF

Many animal populations managed by the Association of Zoos and Aquariums' (AZA) Species Survival Plans® (SSPs) have low rates of reproductive success. It is critical that individuals recommended to breed are successful to achieve genetic and demographic goals set by the SSP. Identifying factors that impact reproductive success can inform managers on best practices and improve demographic predictions.

View Article and Find Full Text PDF

With low levels of human antibiotics in the environment due to release of wastewater treatment plant (WWTP) effluent, concern is rising about impacts on human health and antibiotic resistance development. Furthermore, WWTP effluent may be released into waterways used as drinking water sources. The aim of this study was to analyze three antibiotics important to human health (sulfamethoxazole, ofloxacin, and trimethoprim) in soil and groundwater at a long-term wastewater reuse system that spray irrigates effluent.

View Article and Find Full Text PDF

Tools to assess the risk of becoming a victim of child sexual exploitation (CSE) have been developed by UK CSE practitioners based on their professional experiences, with little evidence underpinning their development, and no evaluation/validation. Little is known about how they are used in practice. This paper summarizes two studies.

View Article and Find Full Text PDF

We investigated the adsorption and oxidation of n-propane and cyclopropane (C3H8 and c-C3H6) on the IrO2(110) surface using temperature programmed reaction spectroscopy (TPRS) and density functional theory (DFT) calculations. We find that the activation of both C3H8 and c-C3H6 is facile on IrO2(110) at low temperature, and that the dissociated alkanes oxidize during TPRS to produce CO, CO2 and H2O above ∼400 K. Propane conversion to propylene is negligible during TPRS for the conditions studied.

View Article and Find Full Text PDF

Using data on waterfowl band recoveries, we identified spatially explicit hotspots of concentrated waterfowl movement to predict occurrence and spatial spread of a novel influenza A virus (clade 2.3.4.

View Article and Find Full Text PDF

Proper planning and communication between psychiatry and anesthesiology teams is vital to conferring the greatest therapeutic benefit to children presenting for electroconvulsive therapy while minimizing risk. Anesthesia for the child undergoing electroconvulsive therapy should ideally provide deep hypnosis, ensure muscle relaxation to reduce injury, have minimal effect on seizure dynamics, and allow for rapid recovery to baseline neurologic and cardiopulmonary status. Unique factors for pediatric electroconvulsive therapy include the potential need for preoperative anxiolytic and inhalational induction of anesthesia, which must be weighed against the detrimental effects of anesthetic agents on the evoked seizure quality required for a successful treatment.

View Article and Find Full Text PDF

Tissue engineering has offered unique opportunities for disease modeling and regenerative medicine; however, the success of these strategies is dependent on faithful reproduction of native cellular organization. Here, it is reported that ultrasound standing waves can be used to organize myoblast populations in material systems for the engineering of aligned muscle tissue constructs. Patterned muscle engineered using type I collagen hydrogels exhibits significant anisotropy in tensile strength, and under mechanical constraint, produced microscale alignment on a cell and fiber level.

View Article and Find Full Text PDF

This protocol demonstrates a customized bioaerosol sampling method for viruses. In this system, anion exchange resin is coupled with liquid impingement-based air sampling devices for efficacious concentration of negatively-charged viruses from bioaerosols. Thus, the resin serves as an additional concentration step in the bioaerosol sampling workflow.

View Article and Find Full Text PDF

Brentuximab vedotin (Bv) is becoming increasingly important in the treatment of Hodgkin lymphoma (HL), with improved outcomes and an overall favourable toxicity profile. However, Bv is associated with severe pulmonary toxicity when combined with bleomycin, suggesting that additive toxicity may be an important consideration. Furthermore, little has been published on tolerability in paediatric patients.

View Article and Find Full Text PDF

What We Already Know About This Topic: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Complications in pediatric regional anesthesia are rare, so a large sample size is necessary to quantify risk. The Pediatric Regional Anesthesia Network contains data on more than 100,000 blocks administered at more than 20 children's hospitals. This study analyzed the risk of major complications associated with regional anesthesia in children.

View Article and Find Full Text PDF

Background And Objectives: Little is known about opioid prescribing for children without severe conditions. We studied the prevalence of and indications for outpatient opioid prescriptions and the incidence of opioid-related adverse events in this population.

Methods: This retrospective cohort study between 1999 and 2014 included Tennessee Medicaid children and adolescents aged 2 to 17 without major chronic diseases, prolonged hospitalization, institutional residence, or evidence of a substance use disorder.

View Article and Find Full Text PDF

The use of systematic preference assessments can enhance positive reinforcement training with captive animals. We found that the multiple stimulus without replacement (MSWO) technique identified food preferences in laboratory housed rhesus macaques, with raisins and grapes being ranked higher on average than dried apricot, pasta, and green beans (Friedman Test, χ (4) = 35.52, p < .

View Article and Find Full Text PDF

Purpose: This study aimed to correlate sleep profile and behavior in individuals with Specific Learning Disorder (SLD).

Methods: The Sleep General Habits Questionnaire, Sleep Diary, and Sleep Disturbance Scale for Children (SDSC) were used in analysis of sleep, whereas the Child Behavior Checklist (CBCL) inventory was used in analysis of behavior.

Results: 65.

View Article and Find Full Text PDF

Purpose: To investigate the chronic and acute effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on pressure pain thresholds (PPT) in overweight men.

Methods: Twenty-eight participants performed stationary cycling exercise three times per week for 6 weeks. Participants were randomly allocated to HIIT (10 × 1-min intervals at 90% peak heart rate) or MICT (30 min at 65-75% peak heart rate).

View Article and Find Full Text PDF

Porcine epidemic diarrhea virus, a pathogen first detected in US domestic swine in 2013, has rapidly spilled over into feral swine populations. A better understanding of the factors associated with pathogen emergence is needed to better manage, and ultimately prevent, future spillover events from domestic to nondomestic animals.

View Article and Find Full Text PDF