Publications by authors named "Frankie Jones"
Article Synopsis
- - The NCCN Guidelines outline a comprehensive approach to diagnosing, staging, and treating ovarian, fallopian tube, and primary peritoneal cancers.
- - Recent developments in the use of PARP inhibitors, both as maintenance therapy and standalone treatments, have significantly influenced the recommendations in these guidelines.
- - These insights highlight the collaborative effort among experts to continuously update treatment protocols based on the latest research in ovarian cancer therapies.
Article Synopsis
- - Determining the best treatment plan for rectal cancer is complicated, involving choices between curative or palliative surgery and considering impact on bowel function and quality of life, especially for distal rectal cancer patients.
- - Patients with rectal cancer face a higher risk of pelvic recurrence compared to those with colon cancer, making careful patient selection and a multidisciplinary treatment approach essential for better outcomes.
- - Recent updates to the NCCN Guidelines for Rectal Cancer include new treatment options like endoscopic submucosal dissection for early cases, revisions to the total neoadjuvant therapy strategy, and a nonoperative "watch-and-wait" option for patients who respond well to initial therapy.
Colon Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology.
J Natl Compr Canc Netw
June 2024
Article Synopsis
- Colorectal cancer (CRC) ranks as the fourth most common cancer and the second deadliest in the U.S.
- Treatment for advanced metastatic CRC includes multiple active drugs used alone or in combination, depending on patient-specific factors.
- The paper reviews the systemic therapy recommendations for metastatic CRC as outlined in the NCCN Guidelines for Colon Cancer.
Article Synopsis
- Study assessed levels of perfluoroalkyl acids (PFAAs), polybrominated diphenyl ethers (PBDEs), and novel brominated flame retardants (NBFRs) in wastewater lagoons from two high-Arctic and two sub-Arctic communities in Canada to understand local pollution sources.
- The concentrations of PFAAs were similar to lower ends found in temperate regions, while PBDE and NBFR concentrations were notably higher in high-Arctic lagoons, likely due to less dilution from lower potable water use.
- Estimated annual mass effluent loadings to the Arctic via wastewater treatment plants were around 1405 g/year for PFAAs and 549 g/year for PBDEs.