Consensus Guideline for Care of Patients in the Prehospital and Aerospace Settings with Exposures to Hydrazine and Hydrazine Derivatives.

Objectives: Hydrazine (HZ) and Hydrazine Derivative (HZ-D) exposures pose health risks to people in industrial and aerospace settings. Several recent systematic reviews and case series have highlighted common clinical presentations and management strategies. Given the low frequency at which HZ and HZ-D exposures occur, a strong evidence base on which to develop an evidence-based guideline does not exist at this time.

Skin decontamination with and without water irrigation.

Objective: Rinsing only with water or washing with soap and water are common methods of skin decontamination for skin contaminated during a chemical hazard release. The null hypothesis was that a 15-minute water irrigation (decontamination method 1) would not be superior to decontamination using a microfiber towel, followed by a wet wipe (Signature Select Softly Flushable Tissue Better Living Brands LLC, Pleasanton, CA), followed by using another microfiber towel (decontamination method 2).

Methods: A simulated contaminant (Magic Fluorescent Glow Paint for Face and Body, iLC Shenzhen Fulimei Technology Co.

Evaluation of the International Society on Thrombosis and Haemostasis definition of major bleeding in Arizona rattlesnake bites.

Introduction: In 2023, a group of experts proposed that a definition of major bleeding in pharmaceutically anticoagulated patients be used in all snakebite trials. This includes bleeding that results in death, is life-threatening, causes chronic sequelae, or consumes major healthcare resources, including bleeding into a major area or hemoglobin concentration decrease ≥20 g/L. We hypothesized that a decline in hemoglobin concentration ≥20 g/L is common but rarely clinically significant in our population of Arizona rattlesnake bite patients.

Radiation Injuries: Acute Radiation Syndrome in Children.

The conflict in Ukraine has raised the specter of radiological and nuclear incidents, including fighting at the Zaporizhzhia nuclear plant, the largest nuclear powerplant in Europe; concerns that a radiological dispersion device ("dirty bomb") may be used; and threats to deploy tactical nuclear weapons. Children are more susceptible than adults to immediate and delayed radiation health effects. This article reviews the diagnosis and treatment of acute radiation syndrome.

Mixed crystal of bis-(ammonium/oxonium) tetra-aqua-μ-fluorido-dodeca-kis-(μ-tri-fluoro-acetato)-hexa-ytterbiate(III) tetra-hydrate, [(NH) (HO) ][YbF(OCCF)(HO)]·4HO ( = 1/4), containing a hexa-nuclear ytterbium(III) carboxyl-ate complex with face-capping fluoride ligands and comprising an unusual kind of substitutional disorder.

The reaction of ytterbium metal with ammonium tri-fluoro-acetate in liquid ammonia resulted in a green substance comprising a substantial amount of ytterbium(II) tri-fluoro-acetate that is a useful precursor for the oxidative synthesis of the new ytterbium(III) compound, [(NH) (HO) ][YbF(OCCF)(HO)]·4HO ( = 1/4), in aqueous tri-fluoro-acetic acid. This mixed ammonium/oxonium crystalline solid is the first example of a substance containing an -hexa-nuclear ytterbium(III) complex with μ-face-capping fluorido ligands. The main structural features of its [YbF] core are non-bonding Yb⋯Yb distances and Yb-F bond lengths of 3.

Oxidation of europium with ammonium perfluorocarboxylates in liquid ammonia: pathways to europium(II) carboxylates and hexanuclear europium(III) fluoridocarboxylate complexes.

The novel coordination polymer [Eu(OCCF)(dmf)] (1) (dmf = ,-dimethylformamide) containing europium(II) and the two new compounds (NH)[EuF(OCCF)(CFCOOH)] (2) and (NH)[EuF(OCCF)(CFCOOH)]·8CFCOOH (3), both based on hexanuclear europiate(III) complexes, were synthesized from precursors with a Eu : Eu ratio >1, obtained by reaction of europium metal with ammonium perfluorocarboxylates in liquid ammonia. In the crystal structure of 1 the europium(II) ions are bridged by carboxylate groups and ,-dimethylformamide to form polymeric chains with Eu⋯Eu distances of 408.39(13)-410.

Do mnemonics help healthcare professionals learn and recall cholinergic toxidromes?

Background: The U.S. National Library of Medicine and Department of Homeland Security assembled subject matter experts (SMEs) for the Toxic Chemical Syndrome Definitions and Nomenclature Workshop.

Initial Experience with F(ab')2 Antivenom Compared with Fab Antivenom for Rattlesnake Envenomations Reported to a single poison center during 2019.

Background: There are two Food and Drug Administration (FDA)-approved antivenoms available for rattlesnake envenomations in the United States: the equine-derived F (ab')2 product sold with the brand name Anavip (F (ab')2 AV) and the ovine-derived Fab product sold with the brand name Crofab (FabAV).

Objective: To compare the clinical outcomes of rattlesnake envenomation patients treated either with FabAV or F (ab')AV or a combination of these.

Methods: This is a retrospective chart review of all human rattlesnake envenomations requiring antivenom reported to one regional poison control center in 2019.

Availability and use of medications by prehospital providers trained to manage medical complications of patients in hazardous materials incidents.

Introduction: Little is known about prehospital availability and use of medications to treat patients from hazardous materials (hazmat) medical emergencies. The aim of this study was to identify the availability and frequency of use of medications for patients in hazmat incidents by paramedics with advanced training to care for these patients.

Methods: A prospectively validated survey was distributed to United States paramedics with advanced training in the medical management of patients from hazmat incidents who successfully completed a 16-hour Advanced Hazmat Life Support (AHLS) Provider Course from 1999 to 2017.

A dyadic approach toward the interpersonal consequences of time pressure.

Although time pressure can decisively shape employees' behavior, little remains known about the consequences associated with perceptions of time pressure between cooperating individuals. Hence, this investigation uses two experimental studies (across different cultural contexts) to examine the joint role of a focal individual's (i.e.

Transition-metal-free oxidative cyclization reaction of enynals to access pyrane-2-one derivatives.

A novel and efficient metal-free C-H functionalization of enynals is developed to synthesize α-pyrone derivatives via the formation of two C-O bonds. In this project, KSO has been introduced as an efficient oxygen source and C-H functionalization agent in regioselective oxidative cyclization reaction with a relatively broad substrate scope.

Fatal abrin poisoning by injection.

Abrin is a toxin of public health concern due to its lethality, lack of antidote, and potential for use as a bioterrorism agent. Possible routes of exposure include ingestion, inhalation, and injection. Onset of symptoms is often delayed, even in severe cases.

The 'super acid' BFHO stabilized by 1,4-dioxane: new preparative aspects and the crystal structure of BFHO·CHO.

Highly Brønsted-acidic boron trifluoride monohydrate, a widely used 'super acid-catalyst', is a colourless fuming liquid that releases BF at room temperature. Com-pared to the liquid com-ponents, boron trifluoride monohydrate and 1,4-dioxane, their 1:1 adduct, BFHO·CHO, is a solid with pronounced thermal stability (m.p.

Synthesis, detailed geometric analysis and bond-valence method evaluation of the strength of π-arene bonding of two isotypic cationic prehnitene tin(II) complexes: [{1,2,3,4-(CH)CH}SnCl][Cl] ( = Al and Ga).

From solutions of prehnitene and the ternary halides (SnCl)[Cl] ( = Al, Ga) in chloro-benzene, the new cationic Sn-π-arene complexes -poly[[chlorido-aluminate(III)]-tri-μ-chlorido-4':1κ ,1:2κ -[(η-1,2,3,4-tetra-meth-yl-benzene)-tin(II)]-di-μ-chlorido-2:3κ -[(η-1,2,3,4-tetra-methyl-benzene)-tin(II)]-di-μ-chlorido-3:4κ -[chlorido-aluminate(III)]-μ-chlorido-4:1'κ ], [AlSnCl(CH)] , () and -poly[[chlorido-gallate(III)]-tri-μ-chlor-ido-4':1κ ,1:2κ -[(η-1,2,3,4-tetra-methyl-benzene)-tin(II)]-di-μ-chlorido-2:3κ -[(η-1,2,3,4-tetra-methyl-benzene)-tin(II)]-di-μ-chlorido-3:4κ -[chlor-ido-gallate(III)]-μ-chlorido-4:1'κ ], [GaSnCl(CH)] , (), were isolated. In these first main-group metal-prehnitene complexes, the distorted η arene π-bonding to the tin atoms of the SnCl moieties in the centre of [{1,2,3,4-(CH)CH}SnCl][Cl] repeating units (site symmetry ) is characterized by: (i) a significant ring slippage of 0.4 Å indicated by the dispersion of Sn-C distances [: 2.

One-pot activation-alkynylation-cyclization synthesis of 1,5-diacyl-5-hydroxypyrazolines in a consecutive three-component fashion.

A consecutive three-component activation-alkynylation-cyclization reaction of (hetero)aryl glyoxylic acids, oxalyl chloride, arylacetylenes, and hydrazides efficiently forms 1,5-diacyl-5-hydroxypyrazolines in moderate to good yields. The structures were unambiguously corroborated by comprehensive NMR spectroscopy and X-ray structure analyses of selected derivatives.

Crystal engineering with short-chained amphiphiles: deca-sodium octa--butane-sulfonate di-μ-chlorido-bis-[di-chlorido-palladate(II)] tetra-hydrate, a layered inorganic-organic hybrid material.

In the course of crystal-engineering experiments, crystals of the hydrated title salt, Na[PdCl](CHSO)·4HO, were obtained from a water/2-propanol solution of sodium -butane-sulfonate and sodium tetra-chlorido-palladate(II). In the crystal, sodium -butane-sulfonate anions and water mol-ecules are arranged in an amphiphilic inverse bilayered cationic array represented by the formula {[Na(CHSO)(HO)]} . Within this lamellar array: (i) a hydro-philic layer region parallel to the plane is established by the Na cations, the HO mol-ecules (as aqua ligands in κ,κ'-bridging coordination mode) and the OS- groups of the sulfonate ions, and (ii) hydro-phobic regions are present containing all the -butyl groups in an almost parallel orientation, with the chain direction approximately perpendicular to the aforementioned hydro-philic layer.

Crystal structure of 1,3-di--butyl-2-chloro-1,3,2-di-aza-phospho-rinane - a saturated six-membered phospho-rus nitro-gen heterocycle with a partially flattened chair conformation and a long P-Cl bond.

Colourless blocks of 1,3-di--butyl-2-chloro-1,3,2-di-aza-phospho-rinane, CHClNP (), were obtained by sublimation slightly above room temperature. The asymmetric unit of the monoclinic crystal structure of the six-membered -heterocyclic compound is defined by one mol-ecule in a general position. The six-membered ring of the mol-ecule adopts a cyclo-hexane-like chair conformation; the chair at one side is to some extent flattened as a result of the approximately trigonal-planar coordination of both nitro-gen atoms.

Synthesis and crystal structure of 1,3-di--butyl-2-chloro-4,4-diphenyl-1,3,2λ,4-di-aza-phospha-siletidine.

The chemical reaction of di-lithium ,'-di( but-yl)-,-di-phenyl-silanedi-amide and PCl yielded an off-white solid. Sublimation of the crude product under reduced pressure at elevated temperature gave colourless prismatic crystals of the title compound, CHClNPSi, which crystallizes in the non-centrosymmetric monoclinic space group The asymmetric unit of the crystal structure contains one mol-ecule and it is dominated by the central SiNP four-membered ring, which is almost planar with a mean deviation of the atoms from the best plane of 0.014 Å.

The dynamic relationship between multiple team membership and individual job performance in knowledge-intensive work.

Many employees in modern, knowledge-based organizations are concurrently involved in more than one team at the same time. This study investigated whether a within-person change in such individual multiple team membership (MTM) may precede and may be predicted by changes in an employee's overall job performance. We examined this reciprocal relationship using longitudinal archival data from a large knowledge-intensive organization, comprising 1,875 employees and spanning 5 consecutive years.

Trends in overdose-related out-of-hospital cardiac arrest in Arizona.

Aim: Opioid overdose mortality has increased in North America; however, recent regional trends in the proportion of treated overdose-related out-of-hospital cardiac arrest (OD-OHCA) compared to out-of-hospital cardiac arrest of presumed cardiac etiology (C-OHCA) are largely unknown. Our aim is to assess trends in the prevalence and outcomes of OD-OHCAs compared to C-OHCAs in Arizona.

Methods: Statewide, observational study utilizing an Utstein-style database with EMS-first care reports linked with hospital records, and vital statistics data from 2010 to 2015.

Comprehensive Study on Reactions of Group 13 Diyls with Tetraorganodipentelanes.

LGa {L = HC[C(Me)N(2,6- iPrCH)]} reversibly reacts with EPh (E = Sb, Bi) in a temperature-dependent equilibrium reaction with insertion into the E-E bond and formation of LGa(EPh) (E = Sb 1, Bi 2). Analogous findings were observed in the reactions of LGa {L = (CH)NC[N(2,6- iPrCH)]} with ER (R = Ph, Et), yielding LGa(EPh) (E = Sb 3, Bi 4) and LGa(EEt) (E = Sb 5, Bi 6). 1-3 and 5 were isolated by fractional crystallization at low temperature, whereas 4 and 6 could not be isolated in their pure form even at low temperature.

Domino Insertion-Coupling Synthesis of Solid-State Luminescent Propynylidene Indolones.

The compound class of 3-arylpropynylidene indolones, key intermediates in consecutive three-component syntheses of various indole-based chromophores with peculiar emission characteristics, are readily synthesized by a domino insertion-coupling synthesis with an electronically diverse substitution pattern in moderate to excellent yields. The title compounds are formed in E/Z-ratios from 100:0 to 0:100. Besides structure elucidation by NMR-spectroscopy and X-ray structure analysis, DFT calculations have been employed to rationalize the observed stereoselectivity.

From stable Sb- and Bi-centered radicals to a compound with a Ga=Sb double bond.

Neutral stibinyl and bismuthinyl radicals are typically short-lived, reactive species. Here we show the synthesis and solid-state structures of two stable stibinyl [L(Cl)Ga]Sb· 1 and bismuthinyl radicals [L(I)Ga]Bi· 4, which are stabilized by electropositive metal centers. Their description as predominantly metal-centered radicals is consistent with the results of NMR, EPR, SQUID, and DFT studies.

A General Route to Metal-Substituted Dipnictenes of the Type [L(X)M] E.

Two equivalents of LGa (L=HC[C(Me)N(2,6-iPr C H )] ) reacted with PX (X=Cl, Br) with insertion into two P-X bonds and formation of [L(X)Ga] PX (X=Cl 1, Br 2), whereas the analogous reaction with AsCl occurred with twofold insertion and subsequent elimination of LGaCl and formation of the Ga-substituted diarsene [L(Cl)Ga] As (3). Analogous findings were observed in the reactions with Me NAsCl , yielding the unsymmetrically-substituted diarsene [L(Cl)Ga]As=As[Ga(NMe )L] (4). The reaction of As(NMe ) with LGa gave [L(Me N)Ga] As (5) after heating at 165 °C for five days, whereas the reaction with LAl gave [L(Me N)Al] As (6) after heating at only 80 °C for one day.