Thirteen years HIV-1 sentinel surveillance and indicators for behavioural change suggest impact of programme activities in south-west Tanzania.

Objective: To describe the evolution of the HIV-1 epidemic among women attending antenatal clinics in four different geographic areas within two rural regions with differing intervention intensity in south-west Tanzania.

Design And Methods: Age-specific trends in HIV-1 seroprevalence among antenatal clinic attendees in four distinct geographic areas of Mbeya region between 1988 and 2000 and in one area of Rukwa region between 1991 and 1999 were analysed and compared. In Mbeya region a comprehensive AIDS control programme has been implemented since 1988.