Dredged sediments as a plant-growing substrate: Estimation of health risk index.

Dredging of sediments is conducted worldwide to maintain harbours and water bodies. As a result, large amounts of materials generated require proper management and could have useful applications in a circular economy context. The current use of peat as organic material in cultivating plants requires urgent replacement by more sustainable alternatives.

The impact of chronic kidney disease on lower extremity bypass outcomes in patients with critical limb ischemia.

Objective: Patient selection for open lower extremity revascularization in patients with chronic kidney disease (CKD) remains a clinical challenge. This study investigates the impact of CKD on early graft failure, postoperative complications, and mortality in patients undergoing lower extremity bypass for critical limb ischemia.

Methods: The National Surgical Quality Improvement Program database was queried for all patients with critical limb ischemia from 2012 to 2015 who underwent lower extremity bypass using the targeted vascular set.

Phosphorus Leaching from an Organic and a Mineral Arable Soil in a Rainfall Simulation Study.

Phosphorus derived from agricultural systems has been found to cause eutrophication of surface waters. To combat this, the specific location of soil profile P release is necessary for development of effective mitigation strategies. This paper describes a P leaching study of two Swedish arable soils, an organic (Typic Haplosaprist) and a mineral soil (Typic Hapludalf), both with high P content.

Long-Term Outcomes of Fistula First Initiative in an Urban University Hospital-Is It Still Relevant?

Purpose: Dialysis access failure is a major cause of morbidity in patients with end-stage renal disease. The Fistula First Breakthrough Initiative (FFBI) dictates arteriovenous fistulae (AVFs) should be preferred over arteriovenous grafts (AVGs) as first line for surgically placed accesses. The purpose of this study was to compare patency rates of surgical dialysis accesses in our mature, urban population after the FFBI.

Applicability of models to predict phosphorus losses in drained fields: a review.

Most phosphorus (P) modeling studies of water quality have focused on surface runoff loses. However, a growing number of experimental studies have shown that P losses can occur in drainage water from artificially drained fields. In this review, we assess the applicability of nine models to predict this type of P loss.

Temporary femoral artery bifurcation shunting following penetrating trauma.

Penetrating common femoral artery injuries are life-threatening, especially when the femoral bifurcation has been destroyed. In the presence of other associated injuries which preclude immediate definitive vascular reconstruction, temporary arterial shunting may be useful. Presently available shunts, however, are tubular and allow for distal perfusion to only one vessel.

Managing PAD with multiple platelet inhibitors: the effect of combination therapy on bleeding time.

Purpose: Patients with lower-extremity peripheral arterial disease (PAD) face a high risk of cardiovascular morbidity and mortality. Platelet inhibition (PI) significantly reduces this risk. Combination PI is common and increasingly indicated in patients with PAD; however, the effect on platelet function has not been objectively evaluated.

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha.

The possibility that lipid-induced insulin resistance in human muscle is related to alterations in diacylglycerol (DAG)/protein kinase C (PKC) signaling was investigated in normal volunteers during euglycemic-hyperinsulinemic clamping in which plasma free fatty acid (FFA) levels were increased by a lipid/heparin infusion. In keeping with previous reports, rates of insulin-stimulated glucose disappearance (G(Rd)) were normal after 2 h but were reduced by 43% (from 52.7 +/- 8.

Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructible lower extremity ischemia: preliminary results of a phase I trial.

Objective: The objective of this study was to evaluate the safety and tolerance of increasing single and repeated (n = 2) doses of intramuscular naked plasmid DNA encoding for fibroblast growth factor (FGF) type 1 (NV1FGF) administered to patients with unreconstructible end-stage peripheral arterial occlusive disease (PAD). The secondary objectives were to determine the biologic activity of NV1FGF on hemodynamic and clinical parameters associated with improved perfusion.

Methods: Fifty-one patients with unreconstructible peripheral arterial occlusive disease with rest pain or tissue necrosis underwent treatment with intramuscular NV1FGF.