Publications by authors named "Frank S Yenchick"
This covers discovery and mechanistic aspects as well as initial applications of novel ionization processes for use in mass spectrometry that guided us in a series of subsequent discoveries, instrument developments, and commercialization. matrix-assisted ionization on an intermediate pressure matrix-assisted laser desorption/ionization source the use of a laser, high voltages, or any other added energy was simply unbelievable, at first. Individually and as a whole, the various discoveries and inventions started to paint, , an exciting new picture and outlook in mass spectrometry from which key developments grew that were at the time unimaginable, and continue to surprise us in its simplistic preeminence.
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- The paper discusses a new approach to ionization in mass spectrometry (MS) that doesn’t rely on high-energy inputs like voltage or lasers but instead uses sublimation and evaporation processes in a controlled pressure environment.
- It explores how these innovative ionization methods enable the efficient conversion of both volatile and non-volatile compounds from solids and liquids into gas-phase ions, leading to more accurate and reproducible results in MS analysis.
- The research highlights the potential coexistence of traditional and novel ionization techniques in the same mass spectrometer, with a focus on applications such as clinical testing and portable MS technologies, showcasing advancements in the field from 2010 to 2023.