Identifying and Engineering Bottlenecks of Autotrophic Isobutanol Formation in Recombinant by Systemic Analysis.

(, CLJU) is natively endowed producing acetic acid, 2,3-butandiol, and ethanol consuming gas mixtures of CO, CO, and H (syngas). Here, we present the syngas-based isobutanol formation using harboring the recombinant amplification of the "Ehrlich" pathway that converts intracellular KIV to isobutanol. Autotrophic isobutanol production was studied analyzing two different strains in 3-L gassed and stirred bioreactors.

Genome Sequence of the Acetogenic Bacterium Acetobacterium wieringae DSM 1911T.

Here, we report the draft genome sequence of Acetobacterium wieringae DSM 1911, an anaerobic, autotrophic, acetogenic, d,l-lactate-utilizing bacterium. The genome consists of a chromosome (3.88 Mb) and 3,620 predicted protein-encoding genes.