Dental Implants in 18 Patients with Systemic Scleroderma: A Retrospective Radiographic Analysis Over a 5-Year Period with Focus on Marginal Bone Loss.

Purpose: Patients with systemic scleroderma (SSc) often suffer from premature tooth loss. The aim of this study was to radiologically investigate bone loss at dental implants in patients with SSc and compare it with data from the literature on healthy patients.

Materials And Methods: Mesial and distal bone level changes at implants were independently determined on panoramic and intraoral radiographs.

Dental implants in patients suffering from systemic sclerosis: a retrospective analysis of clinical outcomes in a case series with 24 patients.

Purpose: Patients with systemic sclerosis (SSc) often suffer from premature tooth loss. This is a retrospective case series of patients with systemic sclerosis who were treated with dental implants.

Methods: SSc patients treated with at least one dental implant between 5 August 1998 and 31 December 2018 were included in this long-term retrospective study.

Prevalence of Oral and Maxillofacial Disorders in Patients with Systemic Scleroderma-A Systematic Review.

Background: Systematic scleroderma is a rare chronic autoimmune disease of unknown aetiology. The aim of this study was to identify the prevalence of orofacial pathognomonic conditions in patients with systemic scleroderma using only randomised prospective studies that investigated the treatment of oral and maxillofacial changes, highlighted associations between the disease and Sjogren's syndrome, and/or analysed the effect of oral hygiene.

Methods: The literature was systematically reviewed based on Cochrane Library, EMBASE, PubMed, Scopus, and Web of Science articles published up to March 2020.

Guided implant surgery for one-piece ceramic implants: a digital workflow.

Background: Accurate implant placement in the bone is key to successful implant treatment. Once inserted, it can be difficult to correct the orientation of the implant axis, especially of a one-piece implant. Prosthetic-driven digital implant planning in combination with fully guided implant surgery can offer additional safety in such cases.

Emulating the early phases of human tooth development in vitro.

Functional in vitro models emulating the physiological processes of human organ formation are invaluable for future research and the development of regenerative therapies. Here, a developmentally inspired approach is pursued to reproduce fundamental steps of human tooth organogenesis in vitro using human dental pulp cells. Similar to the in vivo situation of tooth initiating mesenchymal condensation, a 3D self-organizing culture was pursued resulting in an organoid of the size of a human tooth germ with odontogenic marker expression.

Sinus Floor Elevation and Augmentation Using Synthetic Nanocrystalline and Nanoporous Hydroxyapatite Bone Substitute Materials: Preliminary Histologic Results.

Purpose: To compare the tissue composition of augmented sites after using two different synthetic bone substitute materials, nanocrystalline and nanoporous hydroxyapatite (HA), for sinus floor elevation and augmentation.

Materials And Methods: Forty-four patients received 88 titanium screw implants (Camlog Promote plus) of 4.3-mm diameter and 11- or 13-mm length, placed simultaneously during sinus floor elevation and augmentation.

Premature exposure of dental implant cover screws. A retrospective evaluation of risk factors and influence on marginal peri-implant bone level changes.

Objectives: The objectives of this study were to identify risk factors associated with the premature cover screw exposure (pCSE) at dental implants and to evaluate the influence of a pCSE on peri-implant marginal bone level (MBL) change compared to non-exposed implants.

Materials And Methods: Retrospective data assessment from 165 patients (mean age = 54.0 ± 14.

Comparative Clinical Study of Conventional Dental Implants and Mini Dental Implants for Mandibular Overdentures: A Randomized Clinical Trial.

Background: Dental implant-retained overdentures have been chosen as the treatment of choice for complete mandibular removable dentures. Dental implants, such as mini dental implants, and components for retaining overdentures, are commercially available. However, comparative clinical studies comparing mini dental implants and conventional dental implants using different attachment for implant-retained overdentures have not been well documented.

Impact of platform switching on marginal peri-implant bone-level changes. A systematic review and meta-analysis.

Objective: To address the focused question, is there an impact of platform switching (PS) on marginal bone level (MBL) changes around endosseous implants compared to implants with platform matching (PM) implant-abutment configurations?

Material And Methods: A systematic literature search was conducted using electronic databases PubMed, Web of Science, Journals@Ovid Full Text and Embase, manual search for human randomized clinical trials (RCTs) and prospective clinical controlled cohort studies (PCCS) reporting on MBL changes at implants with PS-, compared with PM-implant-abutment connections, published between 2005 and June 2013.

Results: Twenty-two publications were eligible for the systematic review. The qualitative analysis of 15 RCTs and seven PCCS revealed more studies (13 RCTs and three PCCS) showing a significantly less mean marginal bone loss around implants with PS- compared to PM-implant-abutment connections, indicating a clear tendency favoring the PS technique.

Impact of implant-abutment connection, positioning of the machined collar/microgap, and platform switching on crestal bone level changes. Camlog Foundation Consensus Report.

Objectives: The aim of this consensus meeting was to assess the impact of implant-abutment connection, positioning of the machined collar/microgap, and platform switching on crestal bone level changes.

Materials And Methods: Two comprehensive systematic reviews were prepared in advance of the meeting. Consensus statements, practical recommendations, and implications for future research were based on within group as well as plenary scrutinization and discussions of these systematic reviews.

Intraoral electrostimulator for xerostomia relief: a long-term, multicenter, open-label, uncontrolled, clinical trial.

Objective: A previous sham-controlled multinational study demonstrated the short-term efficacy and safety for xerostomia treatment of an intraoral device that delivers electrostimulation to the lingual nerve. The objective of this study was to test the hypothesis that those beneficial effects would be sustained over an 11-month period.

Study Design: The device was tested on a mixed sample of 94 patients with xerostomia in an open-label, uncontrolled, prospective multicenter trial.

Implant-prosthetic rehabilitation of the edentulous maxilla and mandible with immediately loaded implants: preliminary data from a retrospective study, considering time of implantation.

Purpose: This study sought to evaluate treatment outcomes of implant-prosthetic rehabilitation with implants in the edentulous maxilla or mandible that were immediately loaded by fixed prostheses. Special consideration was given to the time of implantation (immediate, delayed, or late implant placement).

Materials And Methods: Twenty-five patients who received 283 immediately loaded screw-type implants were included in this retrospective study.

Efficacy and safety of an intraoral electrostimulation device for xerostomia relief: a multicenter, randomized trial.

Objective: To evaluate the efficacy and safety of an intraoral electrostimulation device, consisting of stimulating electrodes, an electronic circuit, and a power source, in treating xerostomia. The device delivers electrostimulation through the oral mucosa to the lingual nerve in order to enhance the salivary reflex.

Methods: The device was tested on a sample of patients with xerostomia due to Sjögren's syndrome and other sicca conditions in a 2-stage prospective, randomized, multicenter trial.

[Electrostimulation for the treatment of dry mouth].

Xerostomia is a very common condition, which not only involves dry mouth feeling, but can also lead to psychosocial distress, impaired quality of life, and complications, such as dental caries and oral candidiasis. It is generally induced by hypofunction of salivary glands, which has a wide variety of etiologies, such as Sjögren's syndrome, radiotherapy to the head and neck and side effects of medications. Current therapies rely on saliva substitutes and pharmacological stimulation of the parasympathetic system.

Lateral alveolar ridge augmentation using a synthetic nano-crystalline hydroxyapatite bone substitution material (Ostim): preliminary clinical and histological results.

Objectives: The purpose of this preliminary two-center clinical prospective study was to evaluate the tissue composition of augmented sites after the use of a nano-crystalline hydroxyapatite (ncHA) bone substitution material by clinical and histological examinations.

Material And Methods: A synthetic ncHA augmentation material was used without any additives in 14 patients requiring lateral ridge augmentation 6-7 months before (10 patients) or at implant placement (four patients). The ncHA material was covered by a titanium mesh for space maintenance.

Oral rehabilitation using Camlog screw-cylinder implants with a particle-blasted and acid-etched microstructured surface. Results from a prospective study with special consideration of short implants.

Objectives: The purpose of the present clinical study was to report on the clinical performance of screw-cylinder implants with special consideration of the survival rate of short implants.

Material And Methods: In this prospective study with consecutive patient recruitment, Camlog screw-cylinder implants with a particle-blasted and acid-etched microstructured surface and a triple-cam tube-in-tube implant-abutment connection have been used only. Two groups of implants were evaluated: implants of 9 and 11 mm in length were considered short, those of 13 and 16 mm were considered long.

Smoking interferes with the prognosis of dental implant treatment: a systematic review and meta-analysis.

Aim: This systematic literature review was performed to investigate if smoking interferes with the prognosis of implants with and without accompanying augmentation procedures compared with non-smokers.

Methods: A systematic electronic and handsearch (articles published between 1989 and 2005; English and German language; search terms "dental or oral implants and smoking"; "dental or oral implants and tobacco") was performed to identify publications providing numbers of failed implants, related to the numbers of smokers and non-smokers for meta-analysis. Publications providing statistically examined data of implant failures or biologic complications among smokers compared with non-smokers were included for systematic review.

Implant-prosthetic treatment in HIV-infected patients receiving highly active antiretroviral therapy: report of cases.

Purpose: Since 1997, the use of highly active antiretroviral therapy (HAART) has significantly improved systemic health and life expectancy of patients who test positive for the human immunodeficiency virus (HIV) in industrialized countries. Therefore, although implant-supported prosthetic rehabilitation has been restricted to immunocompetent individuals, it may be considered for these patients.

Case Reports: The treatment course of implant-prosthetic rehabilitation in 3 patients is reported.

Tissue-engineered bone for lateral alveolar ridge augmentation: a case report.

Bone matrix derived from mandibular periosteal cells and cultivated by tissue engineering on a polymer fleece has recently been used for sinus floor elevation and augmentation. This case report focuses on clinical and histologic results after lateral ridge augmentation of a localized non-space maintaining defect in the right posterior area of the mandible using tissue-engineered bone. Implant supported prosthetic rehabilitation of a partially edentulous 32-year-old woman was planned involving a fixed partial denture.

Healing pattern of bone defects covered by different membrane types--a histologic study in the porcine mandible.

Few investigations on guided bone regeneration (GBR) focus on the behaviour of tissues adjacent to barrier membranes. This study was conducted to (1) evaluate the barrier function potential of different resorbable and nonresorbable membranes for GBR, (2) investigate their structural changes after different intervals, and (3) characterize tissue composition and reaction adjacent to the barrier by qualitative histologic evaluation. Seven barriers for GBR were used per animal (made of dense or expanded polytetrafluoroethylene (d/ePTFE), titanium, polyetherurethane, collagen and two polylactide-polyglycolide-/-trimethylenecarbonate-co-polymers (PLPG, LPGTC) in standardized defects not exceeding the critical size) without using bone substitution material or autogenous bone at the right inferior margin of the mandibles of six domestic pigs.

Retrospective evaluation of the success of oral rehabilitation using the Frialit-2 implant system. Part 1: Influence of topographic and surgical parameters.

Purpose: This retrospective longitudinal study evaluated the success of implant-prosthetic rehabilitation with the Frialit-2 implant system.

Materials And Methods: The study was performed with 504 patients, from two treatment centers, who had received a total of 1,554 implants between May 1990 and May 2001. The data of these patients, who received the implants in various regions and for various indications, were analyzed with respect to clinical, topographic, and radiographic parameters.

Patient's informed consent prior to implant-prosthetic treatment: a retrospective analysis of expert opinions.

Purpose: The purpose of this retrospective analysis of expert opinions was to optimize the level of patient information prior to implant-prosthetic treatment.

Materials And Methods: Twenty-eight expert opinion reports on implant treatment cases compiled between 1996 and August 2001 were analyzed.

Results: Seventy-five percent of all cases subjected to expert opinion reports revealed generally inadequate patient information.

Histological assessment of augmented jaw bone utilizing a new collagen barrier membrane compared to a standard barrier membrane to protect a granular bone substitute material.

Successful bone augmentation requires predictable space maintenance and adequate exclusion of those cells that lack osteogenetic potential from the defect area. Natural bone mineral is considered to be osteoconductive and is used as space maker in combination with membrane barrier techniques. The aim of this study was to compare qualitative histological results achieved by using deproteinized bovine bone mineral (DBBM) as a space maintainer and a new collagen barrier (Ossix, test group) vs.

Peri-implant alveolar bone loss with respect to bone quality after use of the osteotome technique: results of a retrospective study.

Knife-edge configurations or non space-maintaining defects of the alveolar ridge limit the indications for implant-prosthetic rehabilitation. If ridge expansion is required, bone splitting and bone spreading techniques may be applied. Summers introduced a modified approach for ridge expansion by osteotome technique.