Publications by authors named "Frank D Martos-Benitez"
Background And Aims: A recent study reported that Oropouche virus (OROV) infection may play a role in the etiology of Guillain-Barré syndrome. We aimed to identify the neurological performance, disease-modifying therapies, and clinical outcomes related to patients with Oropouche-associated Guillain-Barré syndrome admitted to the critical care unit.
Methods: This was an analysis of 210 patients diagnosed with Guillain-Barré syndrome and suspicion of Oropouche viral infection admitted to the critical care units from June 2024 to September 2024 using the national administrative healthcare data.
Fluid balance, biomarkers of renal function and mortality in critically ill patients with AKI diagnosed before, or within 24 h of intensive care unit admission: a prospective study.
J Nephrol
March 2024
Background: To evaluate fluid balance, biomarkers of renal function and its relation to mortality in patients with acute kidney injury (AKI) diagnosed before, or within 24 h of intensive care unit admission.
Methods: A prospective cohort study considered 773 critically ill patients observed over six years. Pre-intensive care unit-onset AKI was defined as AKI diagnosed before, or within 24 h of intensive care unit admission.
Article Synopsis
- The pandemic spread of SARS-CoV-2 has challenged the scientific community due to the virus's ability to inhibit the body's natural immune response, specifically the interferon response.
- Recombinant interferons, historically effective in treating viral diseases and certain cancers, were initially deployed in China as a treatment and preventive measure for COVID-19, sparking interest among clinicians.
- The review highlights the mechanism of interferons, their interaction with receptors, how coronaviruses disrupt this signaling, and discusses the significance of genes like ACE2, while advocating for the timely use of interferons in COVID-19 treatment.
Article Synopsis
- COVID-19 quickly spread globally, and its connection to chronic health conditions is still under investigation, prompting a study analyzing 65,535 patients in Mexico from January to May 2020 to understand the impact of these comorbidities on patient outcomes.
- The study revealed that chronic comorbidities were present in nearly half of the patients, with significant clinical outcomes like hospital admission and mortality influenced by factors such as age, sex, and specific diseases, though the effects differed between those with and without COVID-19.
- Findings suggest that knowing how chronic conditions affect the severity of COVID-19 can help identify high-risk patients, but further research is needed to confirm these results and explore the unique impacts of specific comorbid
Cancer patients account for 15% of all admissions to intensive care unit (ICU) and 5% will experience a critical illness resulting in ICU admission. Mortality rates have decreased during the last decades because of new anticancer therapies and advanced organ support methods. Since early critical care and organ support is associated with improved survival, timely identification of the onset of clinical signs indicating critical illness is crucial to avoid delaying.
View Article and Find Full Text PDFObjective: To identify the relationship of patient-ventilator asynchrony with the level of sedation and hemogasometric and clinical results.
Methods: This was a prospective study of 122 patients admitted to the intensive care unit who underwent > 24 hours of invasive mechanical ventilation with inspiratory effort. In the first 7 days of ventilation, patient-ventilator asynchrony was evaluated daily for 30 minutes.
Background: The aim of the study was to evaluate the performance of "Acute Physiology and Chronic Health Evaluation II" (APACHE-II), "Simplified Acute Physiology Score 3" (SAPS-3), and "APACHE-II Score for Critically Ill Patients with a Solid Tumor" (APACHE-II) models in cancer patients admitted to ICU.
Methods: Prospective cohort study of 414 patients with an active solid tumor. Discrimination was assessed by area under receiver operating characteristic (AROC) curves and calibration by Hosmer-Lemeshow goodness-of-fit C test (H-L).
Background: Some factors can act on nutritional status of patients operated for a gastrointestinal cancer. A timely and appropriate nutritional intervention could have a positive effect on postoperative outcomes.
Aim: To determine the effect of a program of intestinal rehabilitation and early postoperative enteral nutrition on complications and clinical outcomes of patients underwent gastrointestinal surgery for cancer.
Objectives: To assess correlations among variations in hemodynamic parameters during fluid volume loading.
Material And Methods: Prospective observational study in 2 intensive care units. Sixty patients requiring intravenous fluids underwent challenge tests with 300 mL of crystalloids over a 48-hour period.
Nutritional depletion is commonly observed in patients undergoing surgical treatment for a gastrointestinal malignancy. An appropriate nutritional intervention could be associated with improved postoperative outcomes. The study was aimed to determine the effect of a program of gastrointestinal rehabilitation and early postoperative enteral nutrition upon complications and clinical outcomes in patients who experienced gastrointestinal surgery for cancer.
View Article and Find Full Text PDFPurpose: The study was aimed to describe the characteristics of cancer patients admitted to the oncological ICU and to identify clinical features associated with outcomes.
Methods: This is a prospective study (January 2014 to December 2015) of 522 cancer patients consecutively admitted to the oncological ICU. Patients with a length of oncological ICU stay ≤ 1 day were excluded.
Objective: This study sought to determine the influence of postoperative complications on the clinical outcomes of patients who underwent thoracic and gastrointestinal cancer surgery.
Methods: A prospective cohort study was conducted regarding 179 consecutive patients who received thorax or digestive tract surgery due to cancer and were admitted to an oncological intensive care unit. The Postoperative Morbidity Survey was used to evaluate the incidence of postoperative complications.