Publications by authors named "Frank Adtg Wagener"
Objectives: Dental diseases are a major problem in cats and often necessitate tooth extraction. Medical-grade honey (MGH) has antimicrobial and wound-healing properties, and therefore the aim of this study was to investigate whether intra-socket application improved healing after tooth extraction. It was postulated that applying MGH would reduce inflammation, improve the viability of the surgical flap and enhance healing following tooth extraction.
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- Retinoic acid, an active form of vitamin A, is crucial for embryonic development, but excess levels can disrupt palate formation, leading to cleft palates in mice.
- In a study analyzing mouse embryo palate cultures, retinoic acid treatment showed a significant decrease in palate fusion rates and altered key signaling pathways, particularly increasing WNT signaling.
- The findings indicated that retinoic acid interferes with bone formation and palate development by enhancing WNT pathway activity while downregulating genes involved in bone formation.
Background: Remote ischaemic preconditioning (RIPC) is a strategy to protect a target organ against ischaemia-reperfusion injury (IRI) by inducing short-term ischaemia/reperfusion (I/R) in a remote organ. RIPC of the kidney by temporary limb occlusion would be a safe, inexpensive and noninvasive method to prevent renal damage in, e.g.
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