[How is prostate cancer screening perceived by men 50 to 70 years of age? Analysis based on 1,774 screened individuals].

Introduction: The rationale for mass screening for prostate cancer remains controversial. Apart from the scientific debate, we wanted to evaluate the opinion of prostate cancer screening candidates concerning the practical modalities of this screening and assess the impact of various personal, medical or social factors on their replies.

Material And Method: Following a screening campaign in a French district, 1,774 men, 50 to 70 years of age, who completed screening were interviewed by questionnaire concerning the duration, frequency, mode of blood sampling and the cost of screening.

[Impact of obesity on PSA in prostate cancer screening].

Objective: Obesity is associated with changes of serum levels of androgens and oestrogens which could modulate prostate metabolism. The objective of this study was to investigate a possible correlation between the PSA level and the degree of obesity in a candidate population for prostate cancer screening in order to determine whether the PSA level needs to be adapted before performing biopsy.

Material: During a screening campaign in a French district, serum PSA results and body mass index (BMI) were available for 541 men.

Targeted screening for prostate cancer in high risk families: early onset is a significant risk factor for disease in first degree relatives.

Purpose: Targeted screening for prostate cancer in high risk families is generally suggested by ages 40 to 45 years in first degree relatives. We support this concept by reporting higher risk and earlier onset of the disease in these families.

Materials And Methods: We proposed serum prostate specific antigen (PSA) testing in 40 to 70-year-old first degree relatives of 435 patients with prostate cancer treated between July 1994 and June 1997.