Publications by authors named "Francois-Xavier Lesage"

Article Synopsis
  • - The French Society of Rheumatology and the French Society of Physical Medicine and Rehabilitation aimed to create recommendations for non-drug treatments for knee osteoarthritis due to their inadequate consideration in care.
  • - A systematic review of literature was conducted, followed by discussions among experts to draft and evaluate a list of recommendations for managing knee OA non-pharmacologically.
  • - Five key principles were established, emphasizing a combination of treatments, personalized management, adherence, appropriate exercise, and education, alongside specific recommendations for 11 modalities like braces, physical therapy, and weight loss.
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Objective: We aimed to assess the prevalence of exposure by sector and the sectors of activity most exposed to each exposure, using routine occupational health data, and to quantify the risk of being exposed.

Method: Occupational risk factors were assessed by workers followed by the Occupational Health Service of Cher, using self-reported questionnaires. The sectors of activity were grouped into seven sectors, and the risks were grouped into six occupational exposure groups.

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Background: Despite there is no recommendations for assessing symptoms of sick building syndrome, the use of visual analog scales (VAS) seems attractive and appropriate. We aimed to demonstrate the benefits of using VAS for evaluating subjective symptoms of sick building syndrome.

Method: We compared an exposed group to a control group with a one-year follow-up.

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Background: We aimed to evaluate the prevalence of burnout among French general practitioners in private practice and to study the risk and protective factors of burnout.

Methods: A nationwide cross-sectional study was conducted with French GPs working in a private practice in France who were asked to fulfil an internet questionnaire. We used the secure internet application REDCap.

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Aims: We conducted a cross-sectional study on healthcare workers from the University Hospital in Clermont-Ferrand. They received a self-report questionnaire consisting of the Maslach Burnout Inventory, Job Demand Control Support, Effort-Reward Imbalance model, and questions about ethical conflict in order to investigate on burnout.

Results: We included 1774 workers.

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Objectives: To study the prevalence of burnout among non-health care workers (NHCW), the risk and protective factors and to quantify the risk of burnout.

Method: We conducted a cross-sectional study on the 3142 NHCW of the University Hospital of Clermont-Ferrand. They received a self-assessment questionnaire.

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Objective: Work-related stress is a public health issue. Stress has multiple physical and psychological consequences, the most serious of which are increased mortality and cardiovascular morbidity. The ThermStress protocol was designed to offer a short residential thermal spa program for work-related stress prevention that is compatible with a professional context.

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Immune checkpoint inhibitors (ICI) significantly improve overall survival (OS) in patients with advanced melanoma, but immune-related colitis may occur and warrant anti-tumor necrosis factor α (TNFα) treatment in severe forms. A nationwide, multicenter retrospective survey was conducted to assess both, the real-life incidence of grade 3/4 ICI-induced colitis treated with anti-TNFα, in patients with advanced melanoma, and the consequence of this therapeutic strategy on disease outcome. All patients with advanced melanoma treated with anti-TNFα agents for severe ICI-related colitis in the participating centers were included.

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Psychosocial risks and work suffering. The work related mental disorders are one of the main concerns for physicians and for occupational health policy. In addition of the difficulties to take appropriate preventive measures, due to nature and the complexity of this issue, the mental health and its occupational risk factors certainly need some clarification.

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Objective: The analysis of ill-health related job loss may be a relevant indicator for the prioritization of actions in the workplace or in the field of public health, as well as a target for health promotion. The aim of this study was to analyze the medical causes, the incidence, and the characteristics of employees medically unfit to do their job.

Methods: This one-year prospective study included all workers followed by occupational physicians in an occupational health service in the south of France.

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Background: Mental disorders in the workplace are a major public health problem. Knowledge of the impact of the psychosocial work environment on mental and behavioral disorders can assist occupational physicians in the identification and description of occupational risk situations, and help to define priority actions. However, no classification for occupational exposure factors is currently available.

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Background: Studies of cancer prevalence have produced conflicting results concerning the relative risk of overall and specific sub-types of cancer in patients with multiple sclerosis (MS). Contemporary controls and information on tobacco use and alcohol consumption are generally missing from previous studies.

Objectives: To evaluate lifetime cancer prevalence in a large cohort of MS patients relative to appropriate controls.

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Background: The visual analogue scale (VAS) is widely used in clinical practice by occupational physicians to assess perceived stress in workers. However, a single cut-off (black-or-white decision) inadequately discriminates between workers with and without stress. We explored an innovative statistical approach to distinguish an at-risk population among stressed workers, and to establish a threshold over which an action is urgently required, via the use of two cut-offs.

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Objectives: The aim of this research was to examine the occupational risk factors for Chronic Obstructive Pulmonary Diseases (COPD) in a range of occupations.

Methods: Eleven occupations involving different types of exposure were observed in this multicenter case-control study. Controls and cases were matched for sex, age and smoking.

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Introduction: The diagnoses of workers being unfit to work may be a relevant health indicator. Therefore, the aim of this study was to analyze the one-year incidence of an unfit to work diagnosis.

Method: This one-year prospective study included all workers undergoing annual work medical examination from occupational health services in Troyes, France.

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Background: Creatine is the most widely used supplementation to increase performance in strength; however, the most recent meta-analysis focused specifically on supplementation responses in muscles of the lower limbs without regard to upper limbs.

Objective: We aimed to systematically review the effect of creatine supplementation on upper limb strength performance.

Methods: We conducted a systematic review and meta-analyses of all randomized controlled trials comparing creatine supplementation with a placebo, with strength performance measured in exercises shorter than 3 min in duration.

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Background: Creatine is the most widely used supplementation to increase strength performance. However, the few meta-analyses are more than 10 years old and suffer from inclusion bias such as the absence of randomization and placebo, the diversity of the inclusion criteria (aerobic/endurance, anaerobic/strength), no evaluation on specific muscles or group of muscles, and the considerable amount of conflicting results within the last decade.

Objective: The objective of this systematic review was to evaluate meta-analyzed effects of creatine supplementation on lower limb strength performance.

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Objectives: Only a few studies have analyzed the health of self-employed workers. This cross-sectional study is the first to compare health status among craftsmen joiners and paid joiners.

Material And Methods: Clinical and paraclinical data for self-employed craftsmen and employees were collected by occupational health doctors according to a standardized protocol and compared.

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Objective: Hairdressers have a high incidence of occupational diseases, owing to excessive wet work and exposure to chemical substances. The objective of this study was to assess the prevalence of occupational diseases in a population of self-employed hairdressers, matched for age and sex with a control group of wage-earning hairdressers.

Method: A health questionnaire was administered to both groups by an occupational health practitioner.

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Objectives: Burnout among occupational health physicians in France was measured in a nationwide cross-sectional survey. The relationships between each dimension of burnout (emotional exhaustion, depersonalization, and feelings of low personal accomplishment) and stress level, identity threat, and job characteristics were analysed.

Methods: E-mails were sent out to all occupational physicians working in France by the French Ministry of Labour, inviting them to fill out an online questionnaire.

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