Publications by authors named "Francois Voillet"
Article Synopsis
- The study aims to identify a specific biomarker, N-terminal pro-peptide type III procollagen (NT-PCP-III), that can help detect patients with fibroproliferation after Acute Respiratory Distress Syndrome (ARDS) who may benefit from corticosteroid treatments.
- Researchers included patients with moderate to severe non-resolving ARDS and measured NT-PCP-III levels during lung biopsies, determining a threshold of 9 µg/L for effective diagnosis of fibroproliferation.
- Results showed that patients with NT-PCP-III levels above this threshold had a significantly higher mortality rate, indicating that measuring this biomarker can help identify candidates for potential therapies.
Introduction: Ventilator-associated pneumonia (VAP) may contribute to the mortality associated with acute respiratory distress syndrome (ARDS). We aimed to determine the incidence, outcome, and risk factors of bacterial VAP complicating severe ARDS in patients ventilated by using a strictly standardized lung-protective strategy.
Methods: This prospective epidemiologic study was done in all the 339 patients with severe ARDS included in a multicenter randomized, placebo-controlled double-blind trial of cisatracurium besylate in severe ARDS patients.