Publications by authors named "Francois Libama"

Objective: To review epidemiological surveillance approaches used during Ebola and Marburg hemorrhagic fever epidemics in Africa in the past fifteen years. Overall, 26 hemorrhagic epidemic outbreaks have been registered in 12 countries; 18 caused by the Ebola virus and eight by the Marburg virus. About 2551 cases have been reported, among which 268 were health workers (9,3%).

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Background: Presented here are the results of a comparative trial on the efficacy of three artemisinin-based combinations conducted from May to October 2004, in Pool Province, Republic of Congo.

Methods: The main outcome was the proportion of cases of true treatment success at day 28. Recrudescences were distinguished from re-infections by PCR analysis.

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Background: Patients who have refused to provide blood samples has meant that there have been significant delays in confirming outbreaks of Ebola virus hemorrhagic fever (EVHF). During the 2 EVHF outbreaks in the Republic of Congo in 2003, we assessed the use of oral fluid specimens versus serum samples for laboratory confirmation of cases of EVHF.

Methods: Serum and oral fluid specimens were obtained from 24 patients with suspected Ebola and 10 healthy control subjects.

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Article Synopsis
  • The report outlines the first confirmed outbreak of human monkeypox in the Republic of Congo, involving 11 cases all among children under 18, primarily located around a government hospital in Impfondo.
  • Various diagnostic methods were utilized to identify monkeypox virus infections in individuals showing severe clinical symptoms, resulting in one death and one case with long-term health effects.
  • This outbreak signifies the longest documented continuous human-to-human transmission of monkeypox, suggesting potential changes in how the virus adapts to human hosts.
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