The study aimed to evaluate the Penh index as a potential screening tool for airway reactivity and lung response to endotoxins in piglets.
Researchers measured Penh in both freely moving and anesthetized piglets while exposing them to acetylcholine and endotoxins, observing that Penh increased significantly with both challenges.
The findings suggest that Penh can effectively indicate airway reactivity and changes in lung function during cholinergic and endotoxin exposure in piglets.