Publications by authors named "Francois Desangles"
DosiKit is a new field-radiation biodosimetry immunoassay for rapid triage of individuals exposed to external total-body irradiation. Here, we report on the validation of this immunoassay in human blood cell extracts 0.5 h after in vitro exposure to Cs gamma rays, using γ-H2AX analysis.
View Article and Find Full Text PDFPurpose: RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation.
View Article and Find Full Text PDFIn case of a mass casualty radiation event, there is a need to distinguish total-body irradiation (TBI) and partial-body irradiation (PBI) to concentrate overwhelmed medical resources to the individuals that would develop an acute radiation syndrome (ARS) and need hematologic support (i.e., mostly TBI victims).
View Article and Find Full Text PDFArticle Synopsis
- - The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer-reviewed online resource that focuses on genes related to cancer and hereditary diseases, offering a wealth of information, including review articles and extensive iconography.
- - It integrates various types of data such as genetic abnormalities, histopathology, and clinical diagnoses, evolving from traditional methods to advanced techniques like massive sequencing for more comprehensive insights.
- - This resource serves as a valuable tool for researchers and clinicians, aiding in cytogenetic diagnosis and informing treatment decisions, especially for rare diseases.
Article Synopsis
- * A first-generation cytogenetic diagnostic test using four-color fluorescence in situ hybridization (FISH) was created to identify different RCC subtypes from a single slide.
- * This new FISH technique proved to be highly sensitive in detecting chromosomal abnormalities, including cases missed by traditional methods, making it a valuable tool in RCC diagnosis.