Publications by authors named "Francois Bronner"
Background: The value of prehospital initiation of glycoprotein IIb/IIIa inhibitors remains a controversial issue. We sought to investigate whether in-ambulance initiation of abciximab in patients with ST-segment elevation myocardial infarction (STEMI) improves ST-segment elevation resolution (STR) after primary percutaneous coronary intervention (PCI).
Methods And Results: MISTRAL (Myocardial Infarction with ST-elevation Treated by Primary Percutaneous Intervention Facilitated by Early Reopro Administration in Alsace) is a prospective, randomized, double-blind study.
Article Synopsis
- The study focuses on patients over 75 years old with sinus node dysfunction who received pacemakers, aiming to understand their outcomes such as heart failure, atrial fibrillation, and mortality rates.
- Out of 102 patients followed for about 806 days, 35.3% faced heart failure, 46.1% had paroxysmal atrial fibrillation, and 28.4% died, with nearly half of the deaths being cardiac-related.
- The results indicate that patients with dual-chamber pacemakers that minimize ventricular pacing had significantly lower rates of heart failure and overall mortality compared to those with conventional pacing, suggesting that this approach is beneficial for older patients.